SCHEMBL810567

SCHEMBL810567

[CH](c1ccccc1)c1ccc2ccccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.68
ALDH1A1 P00352 4/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
KDM4E B2RXH2 2/20 0.52
PTGS1 P23219 1/20 0.48
MAPT P10636 3/20 0.46
NQO2 P16083 2/20 0.46
GLA P06280 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
GRIN2D O15399 2/20 0.44
GRIN3B O60391 2/20 0.44
GRIN1 Q05586 2/20 0.44
GRIN2A Q12879 2/20 0.44
GRIN2B Q13224 2/20 0.44
GRIN2C Q14957 2/20 0.44
GRIN3A Q8TCU5 2/20 0.44
GAA P10253 2/20 0.43
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
THRB P10828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2838139 0.93 RELA (0.62) RELAALDH1A1L3MBTL1KDM4EPTGS1
SCHEMBL27781109 0.88 RELA (0.58) RELAALDH1A1L3MBTL1KDM4EPTGS1
SCHEMBL10466215 0.85 CYP1A2 (0.58) RELAALDH1A1L3MBTL1KDM4EPTGS1
SCHEMBL4800219 0.83 CYP1A1 (0.49) RELAALDH1A1L3MBTL1KDM4EPTGS1
SCHEMBL8521001 0.81 CYP1A2 (0.61) RELAALDH1A1L3MBTL1PTGS1NQO2
SCHEMBL30507765 0.81 RELA (1.00) RELAALDH1A1L3MBTL1KDM4EPTGS1
SCHEMBL5407847 0.81 RELA (1.00) RELAALDH1A1L3MBTL1KDM4EPTGS1
SCHEMBL3984479 0.81 RELA (1.00) RELAALDH1A1L3MBTL1KDM4EPTGS1
SCHEMBL5407848 0.81 RELA (1.00) RELAALDH1A1L3MBTL1KDM4EPTGS1
SCHEMBL2357484 0.79 ALDH1A1 (0.50) RELAALDH1A1L3MBTL1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104892471-B Substance having protein tyrosine kinase inhibitory activity, preparation method and use thereof 中国人民解放军军事医学科学院放射与辐射医学研究所 2020-03-27 CN claimed
US-5726306-A INHIBITORS OF SQUALENE SYNTHETASE AND FUNGAL GROWTH; USEFUL IN TREATING AND PREVENTING HYPERLIPIDEMIA TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1998-03-10 US claimed
CN-110099966-B Colorant composition, colorant dispersion liquid, photosensitive resin composition, color filter and liquid crystal display device 株式会社LG化学 2024-05-07 CN disclosed
CN-111527075-B Xanthene compound, photosensitive resin composition containing same, photosensitive material, color filter, and display device 株式会社LG化学 2024-03-15 CN disclosed
US-11236061-B2 Xanthene-based compound and photosensitive resin composition comprising same LG CHEM, LTD. (KR) 2022-02-01 US disclosed
CN-111051439-B Xanthene-based compound and photosensitive resin composition comprising the same 株式会社LG化学 2021-11-16 CN disclosed
CN-110337467-B Method for preparing colorant composition and colorant composition prepared thereby 株式会社LG化学 2021-08-27 CN disclosed
CN-107743487-B Xanthene compound and photosensitive resin composition containing same 株式会社LG化学 2021-08-20 CN disclosed
US-11091644-B2 Method for producing colorant composition, and colorant composition, colorant dispersion, photosensitive resin composition, color filter, liquid crystal display device produced using same LG CHEM, LTD. (KR) 2021-08-17 US disclosed
EP-2962992-B1 FULLERENE DERIVATIVE, ORGANIC SOLAR CELL USING SAME, AND MANUFACTURING METHOD THEREOF LG CHEMICAL LTD (KR) 2021-07-07 EP disclosed
EP-3124519-B1 COPOLYMER AND ORGANIC SOLAR CELL COMPRISING SAME LG CHEMICAL LTD (KR) 2021-05-05 EP disclosed
US-6057290-A ADMINISTERING A CYSTEINE PROTEASE INHIBITOR TO A PATIENT FOR INHIBITING ANGIOGENESIS SENJU PHARMACEUTICAL CO., LTD. (JP) 2000-05-02 US disclosed
US-5508273-A ARALKYLPHOSPHONATES FOR OSTEOPOROSIS ORTHO PHARMACEUTICAL CORPORATION (US) 1996-04-16 US disclosed
EP-0260996-B1 HEAT-SENSITIVE RECORDING MATERIAL CONTAINING COLOR FORMING COMPONENTS FUJI PHOTO FILM CO., LTD. (JP) 1992-07-22 EP disclosed
US-4918047-A CONTAINING OXYSALICYLIC ACID DERIVATIVE AND ZINC COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-04-17 US disclosed
US-4892887-A ANTITUMOR YALE UNIVERSITY (US) 1990-01-09 US disclosed
US-4742041-A DYE PRECURSOR, PROTECTIVE COATING FUJI PHOTO FILM CO., LTD. (JP) 1988-05-03 US disclosed
US-4684747-A ANTITUMOR, ALKYLATING AGENTS YALE UNIVERSITY (US) 1987-08-04 US disclosed
US-4418133-A Disazo photoconductive material and electrophotographic photosensitive member having disazo pigment layer CANON KABUSHIKI KAISHA (JP) 1983-11-29 US disclosed
US-4061746-A Lactamimide inhibitors of gastrointestinal hypersecretion RICHARDSON-MERRELL INC. (US) 1977-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11236061-B2 Xanthene-based compound and photosensitive resin composition comprising same RER1, TAS1R1, SUN2 RELA 3003/4885ALDH1A1 1289/4885L3MBTL1 4650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.