SCHEMBL4081893

SCHEMBL4081893

Fc1cccc(F)c1[N]c1c(F)cccc1F

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.39
CES1 P23141 3/20 0.39
ACHE P22303 1/20 0.36
NFE2L2 Q16236 4/20 0.35
BCHE P06276 1/20 0.35
ALB P02768 1/20 0.32
ERN1 O75460 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PARP1 P09874 1/20 0.31
TAAR1 Q96RJ0 2/20 0.31
PKM P14618 1/20 0.31
PKLR P30613 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL38659149 0.80 ALDH1A1 (0.43) CES2CES1ACHENFE2L2BCHE
SCHEMBL10820270 0.75 CES2 (0.36) CES2CES1ACHENFE2L2BCHE
SCHEMBL1547829 0.75 ACHE (0.39) CES2CES1ACHENFE2L2BCHE
SCHEMBL363206 0.75 CES2 (0.36) CES2CES1ACHENFE2L2BCHE
SCHEMBL835486 0.75 CES2 (0.42) CES2CES1ACHEBCHEALB
SCHEMBL5015496 0.72 CES2 (0.43) CES2CES1ACHENFE2L2BCHE
SCHEMBL29618976 0.72 CES2 (0.43) CES2CES1ACHENFE2L2BCHE
SCHEMBL162206 0.69 GABRA1 (0.50) CES2CES1BCHEALBERN1
SCHEMBL15155678 0.69 CES2 (0.32) CES2CES1
SCHEMBL8105795 0.69 ACHE (0.35) CES2CES1ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2048167-A2 First catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048168-A2 Process for producing catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048170-A2 Second catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
EP-2048169-A2 Third catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer Sumitomo Chemical Company, Limited (JP) 2009-04-15 EP disclosed
US-6914108-B2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-05 US disclosed
US-20030203810-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-30 US disclosed
US-6586356-B2 Coordination catalyst SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-01 US disclosed
US-20010020075-A1 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-09-06 US disclosed
EP-1113026-A2 Catalyst component for addition polymerization, catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-04 EP disclosed