Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | RAD51 | Q06609 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | RAC1 | P63000 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102003 | 0.85 | PKM (0.44) | CTRCCYP1A2RAD51NPC1RAB9A | |
| SCHEMBL8108277 | 0.84 | RAD51 (0.55) | RAD51NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL8099799 | 0.83 | NPC1 (0.51) | RAD51NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL8101679 | 0.82 | MEN1 (0.53) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL7913582 | 0.81 | KDM4E (0.51) | RAD51NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL8108178 | 0.81 | NPC1 (0.47) | RAD51NPC1RAB9AALDH1A1 | |
| SCHEMBL8100020 | 0.81 | RAD51 (0.49) | RAD51NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL8092328 | 0.80 | KDM5B (0.47) | RAD51NPC1RAB9AKDM4EMEN1 | |
| SCHEMBL8102012 | 0.80 | KDM5B (0.48) | CYP1A2RAD51NPC1RAB9AKDM4E | |
| SCHEMBL8108176 | 0.78 | KDM4E (0.56) | CTRCCYP1A2RAD51NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6071930-A | FOR INHIBITION OF MITOSIS OR TUMOR GROWTH | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2000-06-06 | — | — | US | disclosed |
| US-5994367-A | PREVENT CELL MITOSIS; ANTICARCINOGENIC AGENTS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1999-11-30 | — | — | US | disclosed |