Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316094 | 0.79 | ADRA2A (0.51) | BRD4LMNACYP2C19KMT2AMEN1 | |
| SCHEMBL8107425 | 0.79 | ADRA2A (0.51) | BRD4LMNACYP2C19KMT2AMEN1 | |
| SCHEMBL8103457 | 0.76 | ALDH1A1 (0.44) | POLBALDH1A1CYP1A2DRD2KMT2A | |
| SCHEMBL8093549 | 0.75 | BRD4 (0.39) | BRD4POLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL4321443 | 0.75 | — | — | |
| SCHEMBL23878783 | 0.74 | RAB9A (0.41) | ALDH1A1LMNATDP1KMT2AMPO | |
| SCHEMBL29397172 | 0.74 | RAB9A (0.41) | ALDH1A1LMNATDP1KMT2AMPO | |
| SCHEMBL8107564 | 0.74 | ADRA2A (0.47) | BRD4LMNACYP2C9CYP2C19KMT2A | |
| SCHEMBL8101327 | 0.73 | BRD4 (0.39) | BRD4POLBALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8093557 | 0.72 | CYP2D6 (0.51) | POLBALDH1A1LMNATDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127369-A | 5,10-dihydrodipyrido[2,3-b:2,3-e]pyrazin and 5,10-dihydrodipyrido[2,3-b:3,2-e]pyrazin compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |