Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 11/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103219 | 0.80 | ADORA3 (0.39) | BRD4MEN1KMT2A | |
| SCHEMBL6960699 | 0.78 | CYP3A4 (0.52) | PTGER4BRD4CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8101449 | 0.74 | MYC (0.40) | MEN1KMT2A | |
| SCHEMBL8101368 | 0.74 | TRIM24 (0.39) | BRD4MEN1KMT2ACYP2A6KDM4E | |
| SCHEMBL8109276 | 0.71 | ALDH1A1 (0.46) | BRD4MEN1KMT2ACYP2A6KDM4E | |
| SCHEMBL7468232 | 0.67 | ADRA2A (0.33) | BRD4MEN1KMT2A | |
| SCHEMBL7473528 | 0.67 | CHRM2 (0.35) | MEN1KMT2A | |
| SCHEMBL7468021 | 0.65 | CHRM2 (0.39) | — | |
| SCHEMBL8103450 | 0.65 | CHRM2 (0.42) | — | |
| SCHEMBL1289832 | 0.65 | KDM4E (0.42) | PTGER4MEN1KMT2ACYP2A6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127369-A | 5,10-dihydrodipyrido[2,3-b:2,3-e]pyrazin and 5,10-dihydrodipyrido[2,3-b:3,2-e]pyrazin compounds | ADIR ET COMPAGNIE (FR) | 2000-10-03 | — | — | US | disclosed |