SCHEMBL81078

SCHEMBL81078

CCCCCCCCCCCCOCC(O)C[S+](CC)CCCOP(=O)(O)O

nearest known ligand 0.63

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LPAR5 Q9H1C0 5/20 0.63
LPAR3 Q9UBY5 13/20 0.53
LPAR1 Q92633 11/20 0.53
LPAR2 Q9HBW0 8/20 0.53
USP2 O75604 1/20 0.46
HTT P42858 1/20 0.44
P2RY10 O00398 2/20 0.42
LPAR6 P43657 4/20 0.40
LPAR4 Q99677 4/20 0.40
ENPP2 Q13822 1/20 0.40
PLA2G2D Q9UNK4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL4001206 0.87 LPAR5 (0.57) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL9717065 0.86 LPAR5 (0.53) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL9717069 0.84 LPAR5 (0.51) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL1569048 0.82 USP2 (0.57) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL10697010 0.80 LPAR5 (0.70) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL258118 0.78 LPAR5 (1.00) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL258032 0.78 LPAR5 (1.00) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL7820593 0.78 LPAR5 (1.00) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL12621099 0.78 LPAR5 (1.00) LPAR5LPAR3LPAR1LPAR2USP2
SCHEMBL258161 0.78 LPAR5 (1.00) LPAR5LPAR3LPAR1LPAR2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8268765-B2 Mono-, di- and polyol phosphate esters in personal care formulations RHODIA OPERATIONS (FR) 2012-09-18 US claimed
US-7666824-B2 skin wash products that include a skin benefit ingredient, such as a barrier enhancing agent, that can be easily transferred to the skin from the wash product; liquid phase containing sterols and natural fat or oil; microencapsulated KIMBERLY-CLARK WORLDWIDE, INC. (US) 2010-02-23 US claimed
US-7268104-B2 Color changing liquid cleansing products KIMBERLY-CLARK WORLDWIDE, INC. (US) 2007-09-11 US claimed
EP-1678289-B1 BAR SOAP COMPOSITION WITH REDUCED BAR WEAR PROPERTIES COLGATE PALMOLIVE CO (US) 2007-04-11 EP claimed
EP-1395235-B1 SHAMPOOS WITH BEHENYL ALCOHOL COLGATE PALMOLIVE CO (US) 2007-02-28 EP claimed
EP-1678289-A1 BAR SOAP COMPOSITION WITH REDUCED BAR WEAR PROPERTIES Colgate-Palmolive Company (US) 2006-07-12 EP claimed
US-7045491-B2 Bar soap composition with reduced bar wear properties COLGATE-PALMOLIVE COMPANY (US) 2006-05-16 US claimed
WO-2005107691-A1 LAMELLAR STRUCTURED LIQUID CLEANSER COMPOSITIONS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2005-11-17 WO claimed
US-20050239669-A1 skin wash products that include a skin benefit ingredient, such as a barrier enhancing agent, that can be easily transferred to the skin from the wash product; liquid phase containing sterols and natural fat or oil; microencapsulated KIMBERLY-CLARK WORLDWIDE, INC. 2005-10-27 US claimed
WO-2005067875-A1 COLOR CHANGING LIQUID CLEANSING PRODUCTS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2005-07-28 WO claimed
US-20050148490-A1 Color changing liquid cleansing products KIMBERLY-CLARK WORLDWIDE, INC. 2005-07-07 US claimed
US-20050107273-A1 Bar soap composition with reduced bar wear properties COLGATE-PALMOTIVE COMPANY 2005-05-19 US claimed
WO-2005044970-A1 BAR SOAP COMPOSITION WITH REDUCED BAR WEAR PROPERTIES COLGATE-PALMOLIVE COMPANY (US) 2005-05-19 WO claimed
US-6838420-B2 A translucent or transparent composition comprising about 3 to about 40 wt. % soap, about 4 to about 40 wt. % of at least one synthetic surfactant, and water, lower monohydric alcohol, a humectant, a structurant, and gellant are not 0 at the COLGATE-PALMOLIVE COMPANY (US) 2005-01-04 US claimed
EP-0915693-B1 AN OIL-IN-WATER EMULSION FOR USE ON HUMAN SKIN FOR CLEANSING, PRESERVING OR IMPROVING THE CONDITION OF THE SKIN PLUM KEMI PRODUKTION AS (DK) 2003-10-01 EP claimed
US-6608011-B2 Cleaning compounds comprising mixtures of water, stabilizer agent, buffers, preservatives, anionic, nonionic, amphoteric and cationic surfactants used as hair conditioners, soaps or gels COLGATE-PALMOLIVE COMPANY 2003-08-19 US claimed
US-20030130145-A1 Shampoos with behenyl-alcohol COLGATE-PALMOLIVE COMPANY 2003-07-10 US claimed
EP-3743493-B1 SOLIDIFYING LIQUID ANIONIC SURFACTANTS ECOLAB USA INC (US) 2024-07-17 EP disclosed
US-3937807-A BISBIGUANIDE COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1976-02-10 US disclosed
US-3934002-A BIS-GUANIDE THE PROCTER & GAMBLE COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030130145-A1 Shampoos with behenyl-alcohol POLR1C, SMURF1, BSG LPAR5 1249/4885LPAR3 1280/4885LPAR1 1703/4885
US-20050107273-A1 Bar soap composition with reduced bar wear properties DDHD2, SORD, CRABP2 LPAR5 2853/4885LPAR3 3279/4885LPAR1 2427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.