Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | ESRRG | P62508 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | SLC9A5 | Q14940 | 1/20 | 0.31 |
| ▸ | CCR9 | P51686 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108989 | 0.85 | GPR119 (0.35) | KIF11EPHX2EGLN1NR3C2KCNH2 | |
| SCHEMBL8108261 | 0.85 | CYP2C9 (0.34) | KIF11EPHX2ELANEEGLN1MEN1 | |
| SCHEMBL8108723 | 0.83 | KIF11 (0.47) | KIF11EPHX2CACNA1HMEN1MAPT | |
| SCHEMBL8108688 | 0.82 | KIF11 (0.46) | KIF11EPHX2ELANECACNA1HMEN1 | |
| SCHEMBL8108259 | 0.81 | KIF11 (0.33) | KIF11EPHX2MEN1MAPTFPR2 | |
| SCHEMBL8108988 | 0.81 | KIF11 (0.33) | KIF11EPHX2CACNA1H | |
| SCHEMBL8108274 | 0.80 | KIF11 (0.41) | KIF11EPHX2ELANEMEN1MAPT | |
| SCHEMBL8114850 | 0.67 | HRH2 (0.39) | MEN1MAPTFPR2KMT2AMAOA | |
| SCHEMBL8113306 | 0.67 | ALDH1A1 (0.42) | MEN1KMT2A | |
| SCHEMBL8113217 | 0.67 | MAPT (0.45) | ELANEMEN1MAPTFPR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987253-A1 | PYRAZOLONE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5968967-A | INHIBIT PLATELET AGGREGATION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-19 | — | — | US | disclosed |