Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108989 | 0.91 | GPR119 (0.35) | MMP2KIF11EGLN1EPHX2 | |
| SCHEMBL8107895 | 0.85 | KIF11 (0.39) | ELANEMMP2KIF11EGLN1MAPT | |
| SCHEMBL8108259 | 0.82 | KIF11 (0.33) | CYP2C9CYP2C19KIF11HRH2HRH1 | |
| SCHEMBL8108274 | 0.82 | KIF11 (0.41) | CYP2C9CYP2C19ELANEKDM4EALDH1A1 | |
| SCHEMBL8108988 | 0.78 | KIF11 (0.33) | KIF11EPHX2 | |
| SCHEMBL8107901 | 0.78 | ITGB3 (0.38) | ELANEHRH2HRH1HRH3MEN1 | |
| SCHEMBL8108723 | 0.76 | KIF11 (0.47) | KIF11MAPTEPHX2MEN1KMT2A | |
| SCHEMBL8108688 | 0.75 | KIF11 (0.46) | ELANEKDM4EALDH1A1KIF11MAPT | |
| SCHEMBL8114850 | 0.71 | HRH2 (0.39) | KDM4EALDH1A1HPGDHRH2HRH1 | |
| SCHEMBL8113306 | 0.71 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987253-A1 | PYRAZOLONE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5968967-A | INHIBIT PLATELET AGGREGATION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-19 | — | — | US | disclosed |