Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8108259 | 0.92 | KIF11 (0.33) | KIF11EPHX2 | |
| SCHEMBL8108989 | 0.82 | GPR119 (0.35) | KIF11GPR119EPHX2CACNA1H | |
| SCHEMBL8107895 | 0.81 | KIF11 (0.39) | KIF11EPHX2CACNA1H | |
| SCHEMBL8108261 | 0.78 | CYP2C9 (0.34) | KIF11EPHX2 | |
| SCHEMBL8108274 | 0.77 | KIF11 (0.41) | KIF11EPHX2 | |
| SCHEMBL8108723 | 0.76 | KIF11 (0.47) | KIF11EPHX2CACNA1H | |
| SCHEMBL8108688 | 0.75 | KIF11 (0.46) | KIF11EPHX2CACNA1H | |
| SCHEMBL8114850 | 0.66 | HRH2 (0.39) | — | |
| SCHEMBL8113306 | 0.66 | ALDH1A1 (0.42) | — | |
| SCHEMBL8113217 | 0.65 | MAPT (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0987253-A1 | PYRAZOLONE DERIVATIVES | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 2000-03-22 | — | — | EP | disclosed |
| US-5968967-A | INHIBIT PLATELET AGGREGATION | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-19 | — | — | US | disclosed |