Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 5/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.59 |
| ▸ | HTR1A | P08908 | 6/20 | 0.56 |
| ▸ | HTR7 | P34969 | 5/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8103844 | 0.94 | HTR2A (0.65) | HTR2ASLC6A4HTR1AHTR7SIGMAR1 | |
| SCHEMBL8103442 | 0.94 | HTR2A (0.68) | HTR2ASLC6A4HTR1AHTR7SIGMAR1 | |
| SCHEMBL8103915 | 0.84 | CTSS (0.60) | HTR2ASLC6A4HTR1AHTR7SIGMAR1 | |
| SCHEMBL8102136 | 0.79 | CTSS (0.67) | HTR2ASLC6A4HTR1AHTR7SIGMAR1 | |
| SCHEMBL8103525 | 0.79 | HTR2A (0.65) | HTR2ASLC6A4HTR1AHTR7SIGMAR1 | |
| SCHEMBL7685556 | 0.78 | KCNH2 (0.64) | HTR2ASLC6A4HTR1AHTR7SIGMAR1 | |
| SCHEMBL7689489 | 0.78 | KCNH2 (0.61) | HTR2ASLC6A4HTR1AHTR7SIGMAR1 | |
| SCHEMBL2927397 | 0.76 | ALDH1A1 (0.77) | HTR1AHTR7SIGMAR1DRD2ALDH1A1 | |
| SCHEMBL11465528 | 0.76 | SIGMAR1 (0.76) | HTR2AHTR1AHTR7SIGMAR1DRD2 | |
| Ammonia Solution, Strong SCHEMBL11284383 | 0.75 | ALDH1A1 (0.75) | HTR1AHTR7SIGMAR1DRD2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057820-A1 | Arylpiperazinylalkyl-3(2H)-pyridazinones as serotonin 5HT and dopamine D2 receptor agonists | FAES, Fabrica Espanola de Productos Quimicos y Farmaceuticos, S.A. (ES) | 2000-12-06 | — | — | EP | claimed |