Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.59 |
| ▸ | RORC | P51449 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10249302 | 0.86 | AAK1 (0.52) | TLR8RORCMAPTTP53KDM4E | |
| SCHEMBL21803210 | 0.76 | ACSS2 (0.55) | TLR8MAPTACSS2KDM4ELMNA | |
| SCHEMBL2335115 | 0.76 | TLR8 (0.91) | TLR8TP53POLBHTTTLR7 | |
| SCHEMBL16512956 | 0.74 | TLR8 (1.00) | TLR8TP53POLBTLR7 | |
| SCHEMBL14112981 | 0.74 | ACSS2 (0.52) | TLR8MAPTACSS2KDM4EALDH1A1 | |
| SCHEMBL19275979 | 0.73 | KDM4E (0.74) | MAPTTP53KDM4EALDH1A1LMNA | |
| SCHEMBL10249212 | 0.73 | NLRP3 (0.59) | TLR8RORCMAPTTP53KDM4E | |
| SCHEMBL23739435 | 0.73 | DYRK1A (0.43) | TLR8RORCMAPTKDM4EALDH1A1 | |
| SCHEMBL15509992 | 0.73 | TLR8 (0.46) | TLR8MAPTTP53ALDH1A1LMNA | |
| SCHEMBL3635568 | 0.73 | RORC (0.49) | RORCMAPTKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037473-A | AS SUNSCREENS IN COSMETIC AND PHARMACEUTICAL PREPARATIONS; FOR ENHANCING PHOTOSTABILITY OF INDUSTRIAL PRODUCTS SUCH AS PAINTS, VARNISHES, PLASTICS, TEXTILES, PACKAGING MATERIALS AND RUBBERS | HAARMANN & REIMER GMBH (DE) | 2000-03-14 | — | — | US | disclosed |
| US-5961960-A | Use of substituted benzazoles as UV absorbers, new benzazoles and processes for their preparation | HAARMANN & REIMER GMBH (DE) | 1999-10-05 | — | — | US | disclosed |
| EP-0843995-A2 | Use of substituted benzazoles as UV absorbents, new benzazoles and their preparation | HAARMANN & REIMER GMBH (DE) | 1998-05-27 | — | — | EP | disclosed |