Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | AHR | P35869 | 2/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | MDM4 | O15151 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.51 |
| ▸ | FABP2 | P12104 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5309687 | 0.79 | ALDH1A1 (0.54) | RAB9AKMT2ALMNAALDH1A1L3MBTL1 | |
| SCHEMBL6544670 | 0.78 | L3MBTL1 (0.67) | NPC1RAB9AKMT2ALMNAMEN1 | |
| SCHEMBL2518715 | 0.78 | PPARA (0.50) | RAB9AKMT2AMEN1PPARAFABP2 | |
| SCHEMBL6058853 | 0.78 | L3MBTL1 (0.72) | NPC1RAB9AKMT2ATP53LMNA | |
| SCHEMBL12099902 | 0.77 | DHODH (0.56) | NPC1RAB9AKMT2ALMNAMEN1 | |
| SCHEMBL8108539 | 0.77 | PPARA (0.65) | NPC1RAB9AKMT2AMEN1PPARA | |
| SCHEMBL10016400 | 0.76 | KMT2A (1.00) | NPC1RAB9AKMT2ATP53LMNA | |
| SCHEMBL9767724 | 0.76 | KMT2A (0.79) | NPC1RAB9AKMT2ATP53LMNA | |
| SCHEMBL12166209 | 0.76 | PPARA (0.69) | NPC1RAB9AKMT2ATP53LMNA | |
| SCHEMBL12017475 | 0.75 | KDM4E (0.57) | KMT2AMEN1PPARAFABP2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140371316-A1 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | FABRICANT JILL S (US) | 2014-12-18 | — | — | US | disclosed |
| EP-2782902-A2 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | Fabricant, Jill, S. (US) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013078446-A2 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | FABRICANT JILL S (US) | 2013-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371316-A1 | DERIVATIVES OF PHENOXYISOBUTYRIC ACID | AGER, BPGM, FOSB | NPC1 4757/4885RAB9A 1613/4885KMT2A 1991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.