Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.70 |
| ▸ | MMP13 | P45452 | 7/20 | 0.70 |
| ▸ | MMP9 | P14780 | 5/20 | 0.70 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.70 |
| ▸ | MMP14 | P50281 | 2/20 | 0.70 |
| ▸ | MMP7 | P09237 | 2/20 | 0.70 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.70 |
| ▸ | MMP8 | P22894 | 1/20 | 0.70 |
| ▸ | MMP2 | P08253 | 2/20 | 0.57 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.57 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.57 |
| ▸ | MMP3 | P08254 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420442 | 0.91 | MMP1 (0.69) | MMP1MMP13MMP9ADAM17MMP14 | |
| SCHEMBL26757902 | 0.90 | MMP1 (0.73) | MMP1MMP13MMP9ADAM17MMP14 | |
| SCHEMBL7417303 | 0.86 | MMP1 (0.68) | MMP1MMP13MMP9ADAM17MMP14 | |
| SCHEMBL31086993 | 0.83 | MMP13 (0.57) | MMP1MMP13MMP9ADAM17MMP14 | |
| SCHEMBL2511972 | 0.83 | MMP9 (0.68) | MMP1MMP13MMP9ADAM17MMP14 | |
| SCHEMBL2511969 | 0.83 | MMP9 (0.68) | MMP1MMP13MMP9ADAM17MMP14 | |
| SCHEMBL7411093 | 0.82 | MMP13 (0.60) | MMP1MMP13MMP9ADAM17MMP14 | |
| SCHEMBL5617679 | 0.82 | ADAM17 (1.00) | MMP1MMP13MMP9ADAM17MMP14 | |
| SCHEMBL3941446 | 0.82 | ADAM17 (1.00) | MMP1MMP13MMP9ADAM17MMP14 | |
| SCHEMBL22889536 | 0.82 | MMP1 (0.66) | MMP1MMP13MMP9ADAM17MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1009737-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999006340-A2 | SULFONYLAMINO SUBSTITUTED HYDROXAMIC ACID DERIVATIVES AS METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |