Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27410866 | 1.00 | TSHR (0.44) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL7463529 | 0.96 | TSHR (0.42) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL8102754 | 0.93 | CTSK (0.42) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL8104481 | 0.90 | CCR2 (0.38) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL8102743 | 0.83 | MAPT (0.45) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL8102739 | 0.83 | MAPT (0.45) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| Trifluoroacetic Acid SCHEMBL8108759 | 0.83 | TSHR (0.47) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| SCHEMBL8108799 | 0.82 | CCR2 (0.34) | CTSK | |
| SCHEMBL8440251 | 0.82 | TSHR (0.46) | TSHRCYP3A4MAPTCYP2C9RAB9A | |
| Trifluoroacetic Acid SCHEMBL7463523 | 0.81 | CTRB1 (0.46) | TSHRCYP3A4MAPTCYP2C9RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6090802-A | BACTERICIDE | SANKYO COMPANY, LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0882728-A1 | 1-METHYLCARBAPENEM DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-09 | — | — | EP | disclosed |