Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7243423 | 0.67 | CYP2C19 (0.50) | CYP2C19TSHRLMNAKMT2AMEN1 | |
| SCHEMBL4123231 | 0.65 | ADAM17 (0.62) | CYP2C19TSHRLMNAADAM17 | |
| SCHEMBL3400918 | 0.65 | ADAM17 (0.62) | CYP2C19TSHRLMNAADAM17 | |
| SCHEMBL2191989 | 0.65 | ADAM17 (0.62) | CYP2C19TSHRLMNAADAM17 | |
| SCHEMBL9737188 | 0.64 | CYP2C19 (0.43) | CYP2C19TSHRLMNAKMT2AMEN1 | |
| Phenylthilone SCHEMBL719266 | 0.64 | KMT2A (0.45) | CYP2C19TSHRLMNAKMT2AMEN1 | |
| SCHEMBL5924439 | 0.64 | CYP2C19 (0.50) | CYP2C19TSHRLMNAKMT2AMEN1 | |
| Mephenytoin SCHEMBL21766 | 0.62 | CYP2C19 (1.00) | CYP2C19TSHRLMNAKMT2AMEN1 | |
| SCHEMBL11255982 | 0.62 | CYP2C19 (0.53) | CYP2C19TSHRLMNAKMT2AMEN1 | |
| Mephenytoin SCHEMBL21768 | 0.62 | CYP2C19 (1.00) | CYP2C19TSHRLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915858-B1 | INTERMEDIATES FOR THE PREPARATION OF 2-IMIDAZOLINE-5-ONES | AVENTIS CROPSCIENCE SA (FR) | 2000-09-13 | — | — | EP | claimed |
| EP-0915858-A1 | INTERMEDIATES FOR THE PREPARATION OF 2-IMIDAZOLINE-5-ONES | Rhone Poulenc Agro (FR) | 1999-05-19 | — | — | EP | claimed |
| WO-1998003490-A1 | INTERMEDIATES FOR THE PREPARATION OF 2-IMIDAZOLINE-5-ONES | RHONE POULENC AGRO (FR) | 1998-01-29 | — | — | WO | claimed |
| EP-0915858-B1 | INTERMEDIATES FOR THE PREPARATION OF 2-IMIDAZOLINE-5-ONES | AVENTIS CROPSCIENCE SA (FR) | 2000-09-13 | — | — | EP | disclosed |
| EP-0915858-A1 | INTERMEDIATES FOR THE PREPARATION OF 2-IMIDAZOLINE-5-ONES | Rhone Poulenc Agro (FR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998003490-A1 | INTERMEDIATES FOR THE PREPARATION OF 2-IMIDAZOLINE-5-ONES | RHONE POULENC AGRO (FR) | 1998-01-29 | — | — | WO | disclosed |