Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19047048 | 0.69 | CHRNB2 (0.40) | CYP2C19TSHRMEN1CYP1A2POLB | |
| SCHEMBL11255982 | 0.67 | CYP2C19 (0.53) | CYP2C19TSHRMEN1CYP1A2POLB | |
| SCHEMBL485258 | 0.65 | LMNA (0.38) | MEN1KMT2ALMNA | |
| SCHEMBL12970866 | 0.64 | CRBN (0.30) | — | |
| SCHEMBL29931742 | 0.64 | ALDH1A1 (0.35) | TSHRMEN1CYP1A2POLBAPEX1 | |
| SCHEMBL8109132 | 0.64 | CYP2C19 (0.45) | CYP2C19TSHRMEN1CYP1A2POLB | |
| SCHEMBL4123231 | 0.63 | ADAM17 (0.62) | CYP2C19TSHRLMNAMAPT | |
| SCHEMBL2191989 | 0.63 | ADAM17 (0.62) | CYP2C19TSHRLMNAMAPT | |
| SCHEMBL3400918 | 0.63 | ADAM17 (0.62) | CYP2C19TSHRLMNAMAPT | |
| SCHEMBL10153059 | 0.63 | TSHR (0.50) | CYP2C19TSHRMEN1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089614-A | Polysubstituted 2-morpholones | THE B. F. GOODRICH COMPANY (US) | 1992-02-18 | — | — | US | disclosed |
| US-4914232-A | FOR POLYMERS | THE B. F. GOODRICH COMPANY (US) | 1990-04-03 | — | — | US | disclosed |
| US-4528370-A | Polysubstituted 2-morpholones | NOVEON IP HOLDINGS CORP., FORMERLY KNOWN AS PMD HOLDINGS CORP. | 1985-07-09 | — | — | US | disclosed |