Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | C1R | P00736 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123575 | 0.89 | FBP1 (0.43) | FBP1SMN1; SMN2CASP3SENP7SENP6 | |
| SCHEMBL8120344 | 0.88 | PTPN22 (0.46) | FBP1SMN1; SMN2CASP3SENP7SENP6 | |
| SCHEMBL8109538 | 0.88 | PRSS1 (0.52) | FBP1SMN1; SMN2CASP3SENP7SENP6 | |
| SCHEMBL8124010 | 0.83 | FBP1 (0.45) | FBP1SMN1; SMN2CASP3SENP7SENP6 | |
| SCHEMBL8124141 | 0.83 | RAB9A (0.39) | FBP1SMN1; SMN2SENP7PKMNPC1 | |
| SCHEMBL8118817 | 0.81 | FBP1 (0.47) | FBP1SMN1; SMN2CASP3SENP7SENP6 | |
| SCHEMBL8124222 | 0.80 | FBP1 (0.74) | FBP1PTPN2PTPN1PTPN5 | |
| SCHEMBL8118348 | 0.80 | FBP1 (0.47) | FBP1SMN1; SMN2CASP3SENP7SENP6 | |
| SCHEMBL8109370 | 0.79 | SMN1; SMN2 (0.56) | FBP1SMN1; SMN2CASP3SENP7SENP6 | |
| SCHEMBL8124732 | 0.77 | FBP1 (0.46) | FBP1SMN1; SMN2CASP3SENP7SENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |