Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193558 | 0.79 | MAPT (0.33) | POLBSMN1; SMN2 | |
| SCHEMBL7694318 | 0.77 | TDP1 (0.37) | TDP1POLBCASP6SRD5A2PTGS1 | |
| SCHEMBL2732652 | 0.76 | KMO (0.39) | TDP1TSHRKMOSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL4777420 | 0.74 | HCAR2 (0.40) | TDP1TSHRKMO | |
| SCHEMBL8101643 | 0.69 | MAPT (0.38) | TDP1SMN1; SMN2 | |
| SCHEMBL1425910 | 0.69 | PIN1 (0.36) | POLBTSHRSMN1; SMN2 | |
| SCHEMBL8109492 | 0.69 | KMO (0.35) | TDP1TSHRKMO | |
| SCHEMBL17674175 | 0.68 | KDM4E (0.47) | TDP1POLBTSHRCASP6SRD5A2 | |
| SCHEMBL7695777 | 0.68 | KMO (0.44) | TDP1KMO | |
| SCHEMBL8110960 | 0.67 | KMO (0.34) | TDP1TSHRKMOSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008383-A1 | LIPOPROTEIN ADSORBENT AND LIPOPROTEIN ADSORBER MADE WITH THE USE OF THE SAME | KANEKA CORPORATION (JP) | 2000-06-14 | — | — | EP | disclosed |