Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MITF | O75030 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | GALR2 | O43603 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8101643 | 0.84 | MAPT (0.38) | MAPTHTTMITFSMN1; SMN2ALDH1A1 | |
| SCHEMBL1425910 | 0.84 | PIN1 (0.36) | MAPTHTTMITFSMN1; SMN2POLB | |
| SCHEMBL27452342 | 0.82 | POLB (0.38) | MAPTHTTMITFSMN1; SMN2POLB | |
| SCHEMBL8110679 | 0.79 | TDP1 (0.36) | SMN1; SMN2POLB | |
| SCHEMBL2042482 | 0.78 | POLB (0.39) | MAPTHTTMITFSMN1; SMN2POLB | |
| SCHEMBL3293002 | 0.69 | PDE10A (0.36) | MAPTHTTMITFSMN1; SMN2POLB | |
| SCHEMBL57064 | 0.69 | — | — | |
| SCHEMBL8665016 | 0.67 | MAPT (0.39) | MAPTHTTSMN1; SMN2POLBPDE10A | |
| SCHEMBL31694393 | 0.67 | PDE10A (0.39) | MAPTSMN1; SMN2POLBPDE10AAPEX1 | |
| SCHEMBL9197442 | 0.67 | ALDH1A1 (0.38) | MAPTPOLBALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7887845-B2 | Particle of a solid dispersion composed of a water soluble polymer and etravirine or salt thereof; etravirine FDA Orange book listed patent | JANSSEN PHARMACEUTICA NV (BE) | 2011-02-15 | — | — | US | disclosed |
| US-20100172970-A1 | ANTIVIRAL COMPOSITIONS | VERRECK GEERT | 2010-07-08 | — | — | US | disclosed |
| US-20070196478-A1 | ANTIVIRAL COMPOSITIONS | VERRECK GEERT | 2007-08-23 | — | — | US | disclosed |
| US-20060127487-A1 | Antiviral compositions | VERRECK GEERT | 2006-06-15 | — | — | US | disclosed |
| EP-1225874-B1 | ANTIVIRAL SOLID DISPERSIONS | JANSSEN PHARMACEUTICA NV (BE) | 2006-02-01 | — | — | EP | disclosed |
| CN-1234347-C | Anti-virus composition | JANSSEN PHARMACEUTICA NV (BE) | 2006-01-04 | — | — | CN | disclosed |
| CN-1376057-A | Anti-virus composition | JANSSEN PHARMACEUTICA NV (BE) | 2002-10-23 | — | — | CN | disclosed |
| EP-1225874-A1 | ANTIVIRAL COMPOSITIONS | Janssen Pharmaceutica N.V. (BE) | 2002-07-31 | — | — | EP | disclosed |
| WO-2001022938-A1 | ANTIVIRAL COMPOSITIONS | JANSSEN PHARMACEUTICA N.V. (BE) | 2001-04-05 | — | — | WO | disclosed |
| US-3755322-A | DIAMINO-S-TRIAZINES | CIBA GEIGY CORP | 1973-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070196478-A1 | ANTIVIRAL COMPOSITIONS | EIF2AK2, ZC3HAV1, RPL35 | MAPT 879/4885HTT 1238/4885MITF 2438/4885 |
| US-20100172970-A1 | ANTIVIRAL COMPOSITIONS | EIF2AK2, ZC3HAV1, RPL35 | MAPT 879/4885HTT 1238/4885MITF 2438/4885 |
| US-20060127487-A1 | Antiviral compositions | EIF2AK2, ZC3HAV1, RPL35 | MAPT 879/4885HTT 1238/4885MITF 2438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.