Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 12/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193558 | 0.84 | MAPT (0.33) | KDM4EHTTSMN1; SMN2LMNAMITF | |
| SCHEMBL8101643 | 0.74 | MAPT (0.38) | KDM4EHTTSMN1; SMN2LMNAMITF | |
| SCHEMBL24238615 | 0.74 | ALDH1A1 (0.44) | PIN1KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL1426637 | 0.74 | ALDH1A1 (0.37) | PIN1KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL8110679 | 0.69 | TDP1 (0.36) | SMN1; SMN2POLBTSHR | |
| SCHEMBL32909 | 0.69 | — | — | |
| SCHEMBL27833684 | 0.69 | NPC1 (0.45) | KDM4EHTTLMNAPOLBMAPT | |
| SCHEMBL1675588 | 0.68 | LMNA (0.35) | PIN1KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL1703418 | 0.68 | TXNRD1 (0.39) | PIN1KDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL28330607 | 0.67 | ALDH1A1 (0.57) | KDM4ESMN1; SMN2LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8680267-B2 | Process for producing amide or lactam | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2014-03-25 | — | — | US | disclosed |
| US-20110092699-A1 | PROCESS FOR PRODUCING AMIDE OR LACTAM | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2011-04-21 | — | — | US | disclosed |
| CN-102026968-A | Process for producing amide or lactam | DAICEL CHEM | 2011-04-20 | — | — | CN | disclosed |
| EP-2301918-A1 | PROCESS FOR PRODUCING AMIDE OR LACTAM | Daicel Chemical Industries, Ltd. (JP) | 2011-03-30 | — | — | EP | disclosed |
| US-20100029931-A1 | METHOD FOR PRODUCING LACTAM COMPOUND | SHIBAMOTO AKIHIRO | 2010-02-04 | — | — | US | disclosed |
| CN-101547896-A | Method for producing lactam compound | DAICEL CHEM (JP) | 2009-09-30 | — | — | CN | disclosed |
| EP-2006283-A9 | PROCESS FOR PRODUCTION OF AMIDES OR LACTAMS | Daicel Chemical Industries, Ltd. (JP) | 2009-07-15 | — | — | EP | disclosed |
| US-20090093628-A1 | Process for Production of Amides or Lactams | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-04-09 | — | — | US | disclosed |
| EP-2006283-A2 | PROCESS FOR PRODUCTION OF AMIDES OR LACTAMS | Mainichi Intecio. (JP) | 2008-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029931-A1 | METHOD FOR PRODUCING LACTAM COMPOUND | COASY, OXA1L, SPOUT1 | PIN1 1260/4885KDM4E 592/4885HTT 4642/4885 |
| US-20090093628-A1 | Process for Production of Amides or Lactams | AFF1, ADH1C, ADH1A | PIN1 2689/4885KDM4E 1900/4885HTT 4843/4885 |
| US-20110092699-A1 | PROCESS FOR PRODUCING AMIDE OR LACTAM | COASY, SULT1A1, SULT2A1 | PIN1 1232/4885KDM4E 2814/4885HTT 4674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.