Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1193558 | 0.84 | MAPT (0.33) | MAPTLMNAHTTALDH1A1HPGD | |
| SCHEMBL1425910 | 0.74 | PIN1 (0.36) | MAPTLMNAHTTALDH1A1KDM4E | |
| SCHEMBL7694321 | 0.74 | LMNA (0.35) | MAPTLMNAHTTALDH1A1TDP1 | |
| SCHEMBL65511 | 0.69 | — | — | |
| SCHEMBL3826741 | 0.68 | ROCK1 (0.39) | MAPTLMNAALDH1A1ROCK1HPGD | |
| SCHEMBL9197442 | 0.68 | ALDH1A1 (0.38) | MAPTLMNAALDH1A1RAB9ATDP1 | |
| SCHEMBL9562215 | 0.67 | HSP90AA1 (0.50) | LMNAHTTRAB9AALOX15KDM4E | |
| Hydrochloric Acid SCHEMBL15477068 | 0.67 | — | — | |
| Water SCHEMBL6396886 | 0.67 | HSP90AA1 (0.50) | MAPTLMNAHTTRAB9AKDM4E | |
| SCHEMBL27452342 | 0.67 | POLB (0.38) | MAPTLMNAHTTALDH1A1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008383-A1 | LIPOPROTEIN ADSORBENT AND LIPOPROTEIN ADSORBER MADE WITH THE USE OF THE SAME | KANEKA CORPORATION (JP) | 2000-06-14 | — | — | EP | disclosed |