Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8127580 | 0.85 | CYP2C19 (0.43) | NOS1SPHK1 | |
| SCHEMBL8112071 | 0.84 | MMP2 (0.39) | ADAM17MMP2 | |
| SCHEMBL8112361 | 0.83 | MC4R (0.34) | ADAM17F2 | |
| SCHEMBL8126529 | 0.82 | MC4R (0.35) | F2 | |
| SCHEMBL8126524 | 0.82 | MC4R (0.35) | F2 | |
| SCHEMBL8119387 | 0.82 | NPY1R (0.45) | NOS1SPHK1MMP2 | |
| SCHEMBL8114860 | 0.82 | SPHK1 (0.43) | NOS1SPHK1DPP7MMP2F2 | |
| SCHEMBL8126777 | 0.81 | PADI6 (0.48) | — | |
| SCHEMBL8112793 | 0.81 | NPY1R (0.54) | — | |
| SCHEMBL8122653 | 0.81 | PADI6 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |