Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.39 |
| ▸ | ADAM10 | O14672 | 3/20 | 0.39 |
| ▸ | MMP9 | P14780 | 3/20 | 0.39 |
| ▸ | ADAM8 | P78325 | 3/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | CCR10 | P46092 | 6/20 | 0.37 |
| ▸ | BMP1 | P13497 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | ADAMTS1 | Q9UHI8 | 1/20 | 0.34 |
| ▸ | ADAMTS7 | Q9UKP4 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8118999 | 0.92 | NPY1R (0.42) | MMP2ADAM17ADAM10MMP9ADAM8 | |
| SCHEMBL8115000 | 0.88 | RAB9A (0.43) | MMP2MMP9MMP12MMP14CCR10 | |
| SCHEMBL8114996 | 0.88 | RAB9A (0.43) | MMP2MMP9MMP12MMP14CCR10 | |
| SCHEMBL8128197 | 0.85 | MMP2 (0.40) | MMP2ADAM17ADAM10MMP9ADAM8 | |
| SCHEMBL8112352 | 0.84 | NOS1 (0.40) | MMP2ADAM17 | |
| SCHEMBL8112361 | 0.82 | MC4R (0.34) | ADAM17 | |
| SCHEMBL8126777 | 0.81 | PADI6 (0.48) | — | |
| SCHEMBL8126524 | 0.81 | MC4R (0.35) | — | |
| SCHEMBL8126529 | 0.81 | MC4R (0.35) | — | |
| SCHEMBL9284142 | 0.81 | PADI6 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |