Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | MC3R | P41968 | 1/20 | 0.35 |
| ▸ | MC1R | Q01726 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.34 |
| ▸ | TLR2 | O60603 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8126529 | 1.00 | MC4R (0.35) | MC4RMC3RMC1RPDCD1CD274 | |
| SCHEMBL8112361 | 0.93 | MC4R (0.34) | MC4RMC3RMC1RPDCD1CD274 | |
| SCHEMBL8115000 | 0.83 | RAB9A (0.43) | RAB9A | |
| SCHEMBL8114996 | 0.83 | RAB9A (0.43) | RAB9A | |
| SCHEMBL8112352 | 0.82 | NOS1 (0.40) | F2 | |
| SCHEMBL9199366 | 0.82 | TLR2 (0.33) | MC4RMC3RMC1RTLR2 | |
| SCHEMBL8112071 | 0.81 | MMP2 (0.39) | — | |
| SCHEMBL8126777 | 0.81 | PADI6 (0.48) | NPY1R | |
| SCHEMBL8112793 | 0.80 | NPY1R (0.54) | NPY1R | |
| SCHEMBL9285714 | 0.80 | NPY1R (0.54) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |