Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12868738 | 0.82 | TXNRD1 (0.41) | LMNASMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL8119056 | 0.76 | MMP9 (0.43) | LMNASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL6593247 | 0.75 | KMT2A (0.40) | LMNASMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL8117700 | 0.74 | POLB (0.41) | LMNASMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL31554662 | 0.72 | LMNA (0.44) | LMNASMN1; SMN2CYP1A2ALDH1A1MAPT | |
| SCHEMBL2966691 | 0.72 | TXNRD1 (0.38) | LMNASMN1; SMN2POLBCYP1A2ALDH1A1 | |
| SCHEMBL30999993 | 0.72 | DYRK1A (0.51) | SMN1; SMN2POLBCYP1A2ALDH1A1MAPT | |
| SCHEMBL27367126 | 0.72 | KMT2A (0.46) | LMNASMN1; SMN2POLBCYP1A2ALDH1A1 | |
| SCHEMBL4040996 | 0.71 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2POLBALDH1A1MAPT | |
| SCHEMBL31165708 | 0.71 | SMN1; SMN2 (0.46) | LMNASMN1; SMN2POLBALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726268-B1 | Substituted benzisoxazole and benzisothiazole herbicidal agents | AMERICAN CYANAMID CO (US) | 2000-11-02 | — | — | EP | disclosed |
| EP-0726268-A1 | Substituted benzisoxazole and benzisothiazole herbicidal agents | American Cyanamid Company (US) | 1996-08-14 | — | — | EP | disclosed |
| US-5523278-A | PRE- AND POST-EMERGENCE HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1996-06-04 | — | — | US | disclosed |
| US-5484763-A | Substituted benzisoxazole and benzisothiazole herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-01-16 | — | — | US | disclosed |