Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.38 |
| ▸ | RARA | P10276 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7564227 | 0.91 | RARA (0.39) | RARBRARAL3MBTL1MEN1KMT2A | |
| SCHEMBL7569104 | 0.89 | RARA (0.38) | RARBRARAL3MBTL1MEN1KMT2A | |
| SCHEMBL8118706 | 0.87 | RXRA (0.44) | RARBRARARARGALOX5PTGS1 | |
| SCHEMBL7563837 | 0.87 | PTGS2 (0.48) | ALOX5PTGS1PTGS2 | |
| SCHEMBL7562951 | 0.86 | MAPT (0.39) | RARBRARAL3MBTL1MEN1KMT2A | |
| SCHEMBL8117130 | 0.85 | RXRA (0.45) | RARBRARAL3MBTL1MEN1KMT2A | |
| SCHEMBL8107672 | 0.78 | RARA (0.38) | RARBRARAL3MBTL1MEN1KMT2A | |
| SCHEMBL7561892 | 0.77 | RXRA (0.43) | RARBRARAL3MBTL1MEN1KMT2A | |
| SCHEMBL7568206 | 0.77 | ALOX5 (0.39) | RARBRARAL3MBTL1MEN1KMT2A | |
| SCHEMBL7570193 | 0.77 | RAB9A (0.47) | L3MBTL1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093838-A | FOR TREATING SKIN-RELATED DISEASES, INCLUDING ACTINIC KERATOSES, ARSENIC KERATOSES, ECZEMA | ALLERGAN SALES, INC. (US) | 2000-07-25 | — | — | US | disclosed |