Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | BMP1 | P13497 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384996 | 0.99 | HRH4 (0.32) | HRH4HRH3HTR1AHTR1DHTR1B | |
| SCHEMBL9850899 | 0.84 | HRH4 (0.40) | HRH4HRH3CYP1A2 | |
| SCHEMBL7625072 | 0.81 | GPR84 (0.42) | HRH4HRH3HTR1AHTR1DHTR1B | |
| SCHEMBL8524329 | 0.81 | HRH4 (0.41) | HRH4HRH3CDK1CCNB1CCNA2 | |
| SCHEMBL7971225 | 0.81 | HRH3 (0.40) | HRH4HRH3HTR1AHTR1DHTR1B | |
| SCHEMBL7976777 | 0.79 | HRH3 (0.38) | HRH4HRH3HTR1AHTR1DHTR1B | |
| SCHEMBL7977147 | 0.78 | HRH4 (0.38) | HRH4HRH3HTR1AHTR1DHTR1B | |
| SCHEMBL4379165 | 0.77 | — | — | |
| SCHEMBL7618097 | 0.77 | HRH4 (0.33) | HRH4HRH3HTR1AHTR1DHTR1B | |
| SCHEMBL7787749 | 0.74 | BMP1 (0.32) | BMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597088-B1 | NOVEL IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THERAPEUTIC APPLICATIONS | INST NAT SANTE RECH MED (FR) | 2000-12-06 | — | — | EP | claimed |