Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8120931 | 0.85 | KDM4E (0.49) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL8120609 | 0.83 | ADRA1A (0.53) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL8105194 | 0.83 | ADRA1D (0.48) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL5042420 | 0.82 | TSHR (0.55) | ALDH1A1LMNAHSD17B10SMN1; SMN2TSHR | |
| SCHEMBL5525906 | 0.80 | CASP3 (0.64) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL8123199 | 0.78 | ALDH1A1 (0.52) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL6903418 | 0.77 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL8116309 | 0.76 | ALDH1A1 (0.66) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| SCHEMBL29483352 | 0.76 | KDM4E (0.65) | ALDH1A1KDM4EHPGDLMNAHSD17B10 | |
| SCHEMBL2442267 | 0.76 | KDM4E (0.65) | ALDH1A1KDM4EHPGDLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |