Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123100 | 0.83 | ALDH1A1 (0.44) | KMT2AMEN1TSHRKDM4ECYP1A2 | |
| SCHEMBL30607253 | 0.81 | ESR1 (0.58) | KMT2AMEN1ESR1ESR2TSHR | |
| SCHEMBL5150486 | 0.81 | ESR1 (0.58) | KMT2AMEN1ESR1ESR2TSHR | |
| SCHEMBL8104888 | 0.79 | PTK2B (0.54) | NPSR1KMT2AMEN1KDM4ECYP1A2 | |
| SCHEMBL29483352 | 0.79 | KDM4E (0.65) | NPSR1KMT2ATSHRKDM4ECYP1A2 | |
| SCHEMBL2442267 | 0.79 | KDM4E (0.65) | NPSR1KMT2ATSHRKDM4ECYP1A2 | |
| SCHEMBL10457215 | 0.79 | KMT2A (0.66) | NPSR1KMT2AMEN1ESR1ESR2 | |
| SCHEMBL8121709 | 0.78 | HSD17B10 (0.54) | KMT2ATSHRKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL28528095 | 0.78 | KDM4E (0.62) | NPSR1KMT2ATSHRKDM4ECYP1A2 | |
| SCHEMBL8107951 | 0.77 | RAB9A (0.49) | KMT2AKDM4ECYP1A2CYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |