Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2B | Q14289 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121709 | 0.88 | HSD17B10 (0.54) | RXFP1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL8107951 | 0.86 | RAB9A (0.49) | KMT2AALDH1A1CYP1A2CYP2C19CYP2C9 | |
| SCHEMBL8116289 | 0.85 | ALOX15 (0.60) | KMT2AMEN1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL25063290 | 0.81 | HSD17B10 (0.58) | PTK2BRXFP1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL208281 | 0.81 | PTK2B (0.70) | PTK2BRXFP1KMT2ANPSR1MEN1 | |
| SCHEMBL8116713 | 0.79 | NPSR1 (0.47) | KMT2ANPSR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL29483352 | 0.79 | KDM4E (0.65) | KMT2ANPSR1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL2442267 | 0.79 | KDM4E (0.65) | KMT2ANPSR1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL28528095 | 0.78 | KDM4E (0.62) | KMT2ANPSR1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL10983921 | 0.77 | PTK2B (0.66) | PTK2BRXFP1KMT2ANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |