Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | IGF1R | P08069 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.41 |
| ▸ | TEK | Q02763 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124637 | 0.83 | RAB9A (0.44) | ALDH1A1HPGDNPC1RAB9AIGF1R | |
| SCHEMBL8123575 | 0.83 | FBP1 (0.43) | FBP1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL8117976 | 0.83 | FBP1 (0.46) | FBP1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL8109370 | 0.82 | SMN1; SMN2 (0.56) | FBP1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL8124732 | 0.81 | FBP1 (0.46) | FBP1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL8125181 | 0.78 | FBP1 (0.72) | FBP1 | |
| SCHEMBL8118817 | 0.77 | FBP1 (0.47) | FBP1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL8118348 | 0.77 | FBP1 (0.47) | FBP1ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL8125598 | 0.75 | PTPN1 (0.48) | FBP1ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL5716848 | 0.74 | CASP3 (0.42) | FBP1ALDH1A1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |