Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.35 |
| ▸ | RELA | Q04206 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124759 | 0.89 | KAT8 (0.39) | RAB9ANPC1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL8124527 | 0.85 | PTPRB (0.43) | MAPTPKMKAT8KMT2ACXCR3 | |
| SCHEMBL8124340 | 0.85 | KAT8 (0.44) | RAB9AKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL8124637 | 0.85 | RAB9A (0.44) | RAB9AKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL8117976 | 0.83 | FBP1 (0.46) | RAB9AKDM4ENPC1ALDH1A1NPSR1 | |
| SCHEMBL8119109 | 0.82 | ALOX15 (0.41) | RAB9AKDM4ENPC1ALDH1A1MAPT | |
| SCHEMBL8126318 | 0.80 | PKM (0.40) | RAB9ANPC1ALDH1A1MAPTNPSR1 | |
| SCHEMBL8109251 | 0.80 | KAT8 (0.38) | RAB9AALDH1A1MAPTPKMKAT8 | |
| SCHEMBL8118852 | 0.78 | MEN1 (0.51) | ALDH1A1MAPTPKMHPGDPPARA | |
| SCHEMBL8125598 | 0.78 | PTPN1 (0.48) | KDM4EALDH1A1MAPTHPGDNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |