Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123201 | 0.92 | LMNA (0.50) | ALDH1A1L3MBTL1TSHRTDP1NPC1 | |
| SCHEMBL2439121 | 0.85 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1TSHRTDP1NPC1 | |
| SCHEMBL8120935 | 0.84 | TSHR (0.66) | ALDH1A1L3MBTL1TSHRTDP1RAB9A | |
| SCHEMBL5540387 | 0.82 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1TSHRTDP1RAB9A | |
| SCHEMBL27903033 | 0.82 | CASP3 (0.45) | ALDH1A1L3MBTL1TSHRTDP1NPC1 | |
| SCHEMBL8115706 | 0.82 | KDM4E (0.52) | ALDH1A1L3MBTL1TSHRTDP1RAB9A | |
| SCHEMBL290777 | 0.81 | TSHR (0.77) | ALDH1A1L3MBTL1TSHRTDP1NPC1 | |
| SCHEMBL8106862 | 0.80 | TSHR (0.67) | ALDH1A1L3MBTL1TSHRTDP1CYP3A4 | |
| SCHEMBL28329024 | 0.80 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1TSHRTDP1NPC1 | |
| SCHEMBL5525906 | 0.79 | CASP3 (0.64) | ALDH1A1TSHRTDP1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114546-A | Aminomethylene derivatives and ultraviolet absorbent comprising thereof | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 2000-09-05 | — | — | US | disclosed |
| EP-0950655-A1 | AMINOMETHYLENE DERIVATIVES AND ULTRAVIOLET ABSORBER COMPRISING THE SAME | CHEMIPRO KASEI KAISHA, LIMITED (JP) | 1999-10-20 | — | — | EP | disclosed |