Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | EDNRA | P25101 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | PPIA | P62937 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8119097 | 0.78 | ALDH1A1 (0.68) | ALDH1A1LMNASMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL8111406 | 0.78 | ALDH1A1 (0.60) | ALDH1A1LMNASMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL848949 | 0.77 | ALDH1A1 (0.91) | ALDH1A1LMNASMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL8117684 | 0.77 | KDM1A (0.69) | LMNAKDM4EMEN1KMT2A | |
| SCHEMBL8110606 | 0.76 | HSD11B1 (0.48) | CYP2C9CYP1A2SCN9A | |
| SCHEMBL3066836 | 0.76 | LMNA (0.79) | ALDH1A1LMNASMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL8110791 | 0.75 | KMO (0.53) | LMNAMEN1KMT2AHTTSCN9A | |
| SCHEMBL184078 | 0.75 | ALDH1A1 (0.72) | ALDH1A1LMNASMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL183995 | 0.75 | ALDH1A1 (0.72) | ALDH1A1LMNASMN1; SMN2KDM4ECYP2C9 | |
| SCHEMBL13180843 | 0.75 | ALDH1A1 (0.72) | ALDH1A1LMNASMN1; SMN2KDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | claimed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | claimed |
| EP-1036069-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-20 | — | — | EP | disclosed |
| WO-1999028306-A1 | BENZENESULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | disclosed |