SCHEMBL8125181

SCHEMBL8125181

O=S(=O)(Nc1nc2cc(Cl)ccc2o1)c1ccc(-c2nc3ccccc3s2)cc1

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ FBP1 P09467 17/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8124222 0.82 FBP1 (0.74) FBP1
SCHEMBL8118910 0.81 ALDH1A1 (0.57) —
SCHEMBL8119318 0.81 FBP1 (0.78) FBP1
SCHEMBL8110017 0.80 FBP1 (0.68) FBP1
SCHEMBL8124010 0.78 FBP1 (0.45) FBP1
SCHEMBL8108185 0.77 FBP1 (0.71) FBP1
SCHEMBL8123406 0.75 FBP1 (0.77) FBP1
SCHEMBL8108924 0.75 FBP1 (0.71) FBP1
SCHEMBL8117894 0.74 FBP1 (0.72) FBP1
SCHEMBL14151271 0.72 FBP1 (0.49) FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1036069-A1 BENZENESULFONAMIDE COMPOUNDS PHARMACIA & UPJOHN S.p.A. (IT) 2000-09-20 — — EP claimed
WO-1999028306-A1 BENZENESULFONAMIDE COMPOUNDS PHARMACIA & UPJOHN S.P.A. (IT) 1999-06-10 — — WO claimed
EP-1036069-A1 BENZENESULFONAMIDE COMPOUNDS PHARMACIA & UPJOHN S.p.A. (IT) 2000-09-20 — — EP disclosed
WO-1999028306-A1 BENZENESULFONAMIDE COMPOUNDS PHARMACIA & UPJOHN S.P.A. (IT) 1999-06-10 — — WO disclosed
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