Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.39 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL812231 | 0.84 | ESR2 (0.49) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL13527344 | 0.83 | ALDH1A1 (0.54) | KDM4EPTGS2CNR2AKR1C3ALDH1A1 | |
| SCHEMBL812302 | 0.83 | EGLN1 (0.41) | KDM4EPTGS2CNR2AKR1C3ALDH1A1 | |
| SCHEMBL14089366 | 0.82 | KDM4E (0.44) | KDM4EPTGS2CNR2AKR1C3ALDH1A1 | |
| SCHEMBL812155 | 0.82 | SHMT1 (0.39) | KDM4EPTGS2ALDH1A1MEN1KMT2A | |
| SCHEMBL812156 | 0.82 | PTGDR2 (0.47) | KDM4EPTGS2AKR1C3ALDH1A1MAPT | |
| SCHEMBL491508 | 0.81 | HSP90AB1 (0.51) | ALDH1A1MAPTMEN1GAAKMT2A | |
| SCHEMBL5535142 | 0.80 | ACLY (0.47) | KDM4EAKR1C3ALDH1A1MAPTEGLN1 | |
| SCHEMBL13359382 | 0.78 | PTGS2 (0.53) | PTGS2CNR2ALDH1A1MEN1GAA | |
| SCHEMBL19068062 | 0.78 | MAPT (0.58) | CNR2ALDH1A1MAPTMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058210-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2011-11-15 | — | — | US | disclosed |
| US-7718706-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-18 | — | — | US | disclosed |
| US-7718706-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-18 | — | — | US | disclosed |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | LIEB FOLKER | 2010-04-08 | — | — | US | disclosed |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | LIEB FOLKER | 2010-04-08 | — | — | US | disclosed |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | LIEB FOLKER | 2008-04-03 | — | — | US | disclosed |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | LIEB FOLKER | 2008-04-03 | — | — | US | disclosed |
| US-7288676-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-10-30 | — | — | US | disclosed |
| US-7288676-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | KCNE1, DDT, KCNQ3 | KDM4E 81/4885PTGS2 1388/4885CNR2 368/4885 |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | KCNE1, DDT, KCNQ3 | KDM4E 81/4885PTGS2 1388/4885CNR2 368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.