Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 9/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121355 | 0.88 | TGM2 (0.42) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL8112530 | 0.85 | OPRM1 (0.44) | FOLH1ANPEPHTTSLC1A3SLC1A1 | |
| SCHEMBL8126909 | 0.79 | CASP1 (0.43) | FOLH1HTTSLC1A3SLC1A1 | |
| SCHEMBL8121290 | 0.78 | SLC1A3 (0.41) | FOLH1ANPEPHTTSLC1A3SLC1A1 | |
| SCHEMBL8112045 | 0.78 | FOLH1 (0.45) | FOLH1ANPEPHTTSLC1A3SLC1A1 | |
| SCHEMBL8119982 | 0.76 | FOLH1 (0.45) | FOLH1ANPEPHTTSLC1A3SLC1A1 | |
| SCHEMBL8119833 | 0.76 | MCHR1 (0.56) | F10PLGPRSS1HTRA1 | |
| SCHEMBL8126814 | 0.75 | FOLH1 (0.48) | FOLH1ANPEPHTTSLC1A3SLC1A1 | |
| SCHEMBL7750702 | 0.74 | F7 (0.43) | F10 | |
| SCHEMBL8120934 | 0.74 | HTT (0.48) | FOLH1ANPEPHTTSLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0680469-B1 | AMINOACID DERIVATES, MEDICAMENTS CONTAINING THESE COMPOUNDS AND PROCESS FOR PREPARING THE SAME | BOEHRINGER INGELHEIM PHARMA (DE) | 2000-04-26 | — | — | EP | disclosed |