Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.73 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.73 |
| ▸ | HPGD | P15428 | 4/20 | 0.73 |
| ▸ | TOP2A | P11388 | 4/20 | 0.60 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | BRD4 | O60885 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TOP1 | P11387 | 1/20 | 0.45 |
| ▸ | ATP6V1B2 | P21281 | 1/20 | 0.44 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8129182 | 0.99 | LMNA (0.75) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Fandofloxacin SCHEMBL1650067 | 0.89 | LMNA (0.74) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Fandofloxacin SCHEMBL1230394 | 0.88 | LMNA (0.73) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL8131363 | 0.88 | ALDH1A1 (0.56) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Fandofloxacin SCHEMBL1650236 | 0.87 | LMNA (0.72) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL8128846 | 0.87 | KDM4E (0.56) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL8134836 | 0.87 | ALDH1A1 (0.58) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL27351294 | 0.86 | ALDH1A1 (0.57) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| SCHEMBL10657099 | 0.85 | ALDH1A1 (0.80) | LMNAALDH1A1KDM4EHSD17B10HPGD | |
| Sarafloxacin SCHEMBL311593 | 0.85 | ALDH1A1 (0.98) | LMNAALDH1A1KDM4EHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713487-B1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM IND CO LTD (KR) | 2000-04-19 | — | — | EP | disclosed |
| CN-1128995-A | Novel Quinolone carboxylic acid derivative | DONG WHA PHARM IND CO LTD (KR) | 1996-08-14 | — | — | CN | disclosed |
| US-5496947-A | BACTERICIDES | DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. (KR) | 1996-03-05 | — | — | US | disclosed |
| WO-1995005373-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES | DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. (KR) | 1995-02-23 | — | — | WO | disclosed |