Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C known ✓ | P18825 | 1/20 | 0.34 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.33 |
| ▸ | ADRA2B known ✓ | P18089 | 1/20 | 0.33 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.33 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.33 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.33 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5292525 | 0.98 | TAAR1 (0.37) | TAAR1RIPK1CYP2D6ADRA2AADRA2C | |
| Iodide SCHEMBL5085038 | 0.96 | TAAR1 (0.35) | TAAR1RIPK1CYP2D6ADRA2AADRA2C | |
| Hydrochloric Acid SCHEMBL5092624 | 0.96 | ALDH1A1 (0.38) | TAAR1RIPK1CYP2D6ADRA2AADRA2C | |
| SCHEMBL7206394 | 0.80 | CYP2D6 (0.40) | TAAR1RIPK1CYP2D6ADRA2AADRA2C | |
| Bromide SCHEMBL7400155 | 0.79 | CYP2D6 (0.36) | TAAR1RIPK1CYP2D6ADRA2AADRA2C | |
| SCHEMBL18729670 | 0.78 | TAAR1 (0.35) | TAAR1RIPK1CYP2D6ADRA2AADRA2C | |
| SCHEMBL27533645 | 0.77 | CYP2D6 (0.43) | TAAR1RIPK1CYP2D6HIF1ACYP1A2 | |
| SCHEMBL6741619 | 0.77 | TAAR1 (0.41) | TAAR1RIPK1CYP2D6ADRA2AADRA2C | |
| SCHEMBL15658444 | 0.76 | — | — | |
| SCHEMBL15656382 | 0.75 | TAAR1 (0.33) | TAAR1RIPK1CYP2D6ADRA2AADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119978028-A | Preparation method of high-temperature-resistant phosphorus salt antistatic agent | 达创新材料科技(山东)有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-112358497-A | Preparation method of polysulfide silane coupling agent with lighter color | 南京曙光精细化工有限公司 | 2021-02-12 | — | — | CN | claimed |
| CN-107353858-B | Packaging adhesive for infrared LED chip and preparation method and application thereof | 广州惠利电子材料有限公司 | 2020-11-10 | — | — | CN | claimed |
| CN-111234185-A | High-crystallinity bifunctional polyester resin for low-temperature curing extinction powder coating and synthesis method thereof | 浙江光华科技股份有限公司 | 2020-06-05 | — | — | CN | claimed |
| CN-111205618-A | Low-temperature impact-resistant high-transmittance flame-retardant polycarbonate composite material and preparation method thereof | 宁波坚锋新材料有限公司 | 2020-05-29 | — | — | CN | claimed |
| US-9522915-B2 | Method for preparing an important intermediate of linagliptin | 2Y-CHEM, LTD. (CN) | 2016-12-20 | — | — | US | claimed |
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | 2Y-CHEM, LTD. (CN) | 2015-10-01 | — | — | US | claimed |
| EP-0764676-B1 | Method of preparing polycarbonate-polysiloxane block copolymers | GEN ELECTRIC (US) | 2004-04-28 | — | — | EP | claimed |
| EP-0010843-B1 | METHOD OF MAKING 5,6-DIHYDRO-2-METHYL-N-PHENYL-1,4-OXATHIIN-3-CARBOXAMIDE | UNIROYAL LTD. (CA) | 1983-11-09 | — | — | EP | claimed |
| US-4247707-A | CATALYTIC LIQUID-PHASE OXIDATION OF 2-METHYL-N-PHENYL-1,3-OXATHIOLANE-2-ACETAMIDE; THEN CATALYTIC THERMAL RING EXPANSION | UNIROYAL CHEMICAL CO./UNIROYAL CHEMICAL CLE. (CA) | 1981-01-27 | — | — | US | claimed |
| EP-0010843-A1 | Method of making 5,6-dihydro-2-methyl-N-phenyl-1,4-oxathiin-3-carboxamide | UNIROYAL LTD. (CA) | 1980-05-14 | — | — | EP | claimed |
| WO-2026087965-A1 | COMPOSITION COMPRISING EPOXY RESIN WITH CONSTRAINED AROMATIC RINGS AND PHOTOBASE | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2026-04-30 | — | — | WO | disclosed |
| US-12479856-B2 | Pharmaceutical compounds for the treatment of complement mediated disorders | ACHILLION PHARMACEUTICALS, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| US-12479781-B2 | Process for the preparation of ethylene glycol | SHELL USA, INC. (US) | 2025-11-25 | — | — | US | disclosed |
| WO-2025200154-A1 | TWO-PART EPOXY COMPOSITION COMPRISING THIOL CURATIVE, AND CATALYST | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2025-10-02 | — | — | WO | disclosed |
| US-4554010-A | 5-Deoxy-3-O-arylmethyl or substituted arylmethyl-1,2-O-substituted-alkylidene-alpha-D-xylofuranose herbicide derivatives | CHEVRON RESEARCH COMPANY (US) | 1985-11-19 | — | — | US | disclosed |
| US-4515618-A | PLANT GROWTH REGULATORS | CHEVRON RESEARCH COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| US-4429119-A | PLANT GROWTH REGULATORS | CHEVRON RESEARCH COMPANY (US) | 1984-01-31 | — | — | US | disclosed |
| US-4247707-A | CATALYTIC LIQUID-PHASE OXIDATION OF 2-METHYL-N-PHENYL-1,3-OXATHIOLANE-2-ACETAMIDE; THEN CATALYTIC THERMAL RING EXPANSION | UNIROYAL CHEMICAL CO./UNIROYAL CHEMICAL CLE. (CA) | 1981-01-27 | — | — | US | disclosed |
| US-4160116-A | FROM THE CORRESPONDING OXIDE BY HYDRATION USING ORGANIC PHOSPHONIUM HALIDE CATALYST, CARBON DIOXIDE | SHOWA DENKO K.K. (JP) | 1979-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12479856-B2 | Pharmaceutical compounds for the treatment of complement mediated disorders | C5, CFH, C1QBP | ADRA2A 2353/4885ADRA2C 1533/4885CHRM2 1468/4885 |
| US-20150274728-A1 | METHOD FOR PREPARING AN IMPORTANT INTERMEDIATE OF LINAGLIPTIN | DPP4, DPP9, DPP3 | ADRA2A 3536/4885ADRA2C 3623/4885CHRM2 4759/4885 |
| US-12479781-B2 | Process for the preparation of ethylene glycol | GYS1, LIPG, LIPE | ADRA2A 2999/4885ADRA2C 3313/4885CHRM2 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.