Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8126751

O=C(O)C(F)(F)F.c1cc(N2CCC(CN3CCNCC3)CC2)ccn1

nearest known ligand 0.48

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.48
NCF1 P14598 1/20 0.48
PLD1 Q13393 1/20 0.48
DPP4 P27487 2/20 0.45
DPP8 Q6V1X1 2/20 0.45
DPP7 Q9UHL4 2/20 0.45
DPP9 Q86TI2 1/20 0.45
ITGB3 P05106 5/20 0.41
ITGA2B P08514 5/20 0.41
SLC2A1 P11166 4/20 0.40
CHRM4 P08173 1/20 0.39
HRH4 Q9H3N8 1/20 0.39
LSS P48449 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP17A1 P05093 1/20 0.39
CYP21A2 P08686 1/20 0.39
CYP11B1 P15538 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29941581 0.88 ADRB2 (0.62) ADRB2NCF1PLD1HRH4ALDH1A1
Trifluoroacetic Acid SCHEMBL1025272 0.80 ITGB3 (0.59) DPP4DPP8DPP7DPP9ITGB3
Trifluoroacetic Acid SCHEMBL6066398 0.80 DPP4 (0.53) DPP4DPP8DPP7DPP9ITGB3
Trifluoroacetic Acid SCHEMBL1456260 0.80 DPP4 (0.53) DPP4DPP8DPP7DPP9ITGB3
Trifluoroacetic Acid SCHEMBL6066623 0.80 DPP4 (0.53) DPP4DPP8DPP7DPP9ITGB3
Trifluoroacetic Acid SCHEMBL4716561 0.79 DPP4 (0.55) DPP4DPP8DPP7DPP9ITGB3
Trifluoroacetic Acid SCHEMBL7017059 0.79 ACHE (0.41) DPP4DPP8DPP7DPP9ITGB3
Trifluoroacetic Acid SCHEMBL30179282 0.77 CACNA2D1 (0.46) ALDH1A1
Trifluoroacetic Acid SCHEMBL30833353 0.76 AR (0.38) DPP4DPP8DPP9HRH4
Trifluoroacetic Acid SCHEMBL1456945 0.76 DPP4 (0.59) DPP4DPP8DPP7DPP9ITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1048652-A1 AROMATIC COMPOUNDS HAVING CYCLIC AMINO OR SALTS THEREOF MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 EP disclosed