Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3324196 | 0.90 | LMNA (0.68) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31143809 | 0.83 | LMNA (0.71) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31143638 | 0.83 | LMNA (0.71) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4070908 | 0.83 | LMNA (0.71) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31143673 | 0.83 | ALDH1A1 (0.71) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19807188 | 0.83 | LMNA (1.00) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19808587 | 0.83 | LMNA (0.51) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9095106 | 0.81 | LMNA (0.60) | LMNAALDH1A1SMN1; SMN2KMT2APNMT | |
| SCHEMBL4066303 | 0.81 | ALDH1A1 (0.56) | LMNAALDH1A1SMN1; SMN2EPHX2PNMT | |
| SCHEMBL21310019 | 0.80 | LMNA (0.68) | LMNAALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230288610-A1 | WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE | FUJIFILM CORPORATION (JP) | 2023-09-14 | — | — | US | disclosed |
| US-10202388-B2 | Fused-ring compounds, pharmaceutical composition and uses thereof | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2019-02-12 | — | — | US | disclosed |
| US-20180022752-A1 | FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-01-25 | — | — | US | disclosed |
| US-20180022752-A1 | FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF | Shanghai De Novo Pharmatech Co., Ltd. (CN) | 2018-01-25 | — | — | US | disclosed |
| EP-3239131-A1 | NEW COMPOUNDS WITH ACTIVITY THAT PROTECTS AGAINST THE ACTION OF TOXINS AND VIRUSES IN INTRACELLULAR ACTION MODE | Commissariat à l'Energie Atomique et aux Energies Alternatives (FR) | 2017-11-01 | — | — | EP | disclosed |
| US-20170233386-A1 | Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-08-17 | — | — | US | disclosed |
| US-20170233386-A1 | Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action | COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-08-17 | — | — | US | disclosed |
| US-9726932-B2 | Optical film, optical compensation film, polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2017-08-08 | — | — | US | disclosed |
| US-9726932-B2 | Optical film, optical compensation film, polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2017-08-08 | — | — | US | disclosed |
| US-9563075-B2 | Method for manufacturing liquid crystal display device provided with front plate, and liquid crystal display device provided with front plate | Konica Minolta, Inc. (JP) | 2017-02-07 | — | — | US | disclosed |
| US-20070252293-A1 | METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM | KONICA MINOLTA OPTO, INC. (JP) | 2007-11-01 | — | — | US | disclosed |
| US-20070252293-A1 | METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM | KONICA MINOLTA OPTO, INC. (JP) | 2007-11-01 | — | — | US | disclosed |
| US-20070195226-A1 | Polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070195226-A1 | Polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070092663-A1 | Cellulose ester film, polarizing plate and display | KONICA MINOLTA OPTO, INC. | 2007-04-26 | — | — | US | disclosed |
| US-20070092663-A1 | Cellulose ester film, polarizing plate and display | KONICA MINOLTA OPTO, INC. | 2007-04-26 | — | — | US | disclosed |
| US-20070076155-A1 | Optical film, optical compensation film, polarizing plate and liquid crystal display | FUJI PHOTO FILM CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| US-20070076155-A1 | Optical film, optical compensation film, polarizing plate and liquid crystal display | FUJI PHOTO FILM CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| US-20070059458-A1 | Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| US-20070059458-A1 | Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display | FUJI PHOTO FILM CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10202388-B2 | Fused-ring compounds, pharmaceutical composition and uses thereof | IDO1, IDO2, TDO2 | LMNA 4813/4885ALDH1A1 2128/4885NPC1 2820/4885 |
| US-20180022752-A1 | FUSED-RING COMPOUNDS, PHARMACEUTICAL COMPOSITION AND USES THEREOF | IDO1, IDO2, TDO2 | LMNA 4813/4885ALDH1A1 2128/4885NPC1 2820/4885 |
| US-20170233386-A1 | Compounds Which Have a Protective Activity with Respect to the Action of Toxins and of Viruses with an Intracellular Mode of Action | HAVCR2, MAVS, ANTXR2 | LMNA 705/4885ALDH1A1 4539/4885NPC1 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.