SCHEMBL3324196

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL812701	0.90	LMNA (0.71)	LMNAALDH1A1PNMTMAPTNPSR1
	Hydrochloric Acid SCHEMBL31732407	0.84	ALDH1A1 (0.49)	LMNAALDH1A1PNMTADAMTS5MAPT
	SCHEMBL31143638	0.81	LMNA (0.71)	LMNAALDH1A1PNMTADAMTS5MAPT
	SCHEMBL31143673	0.81	ALDH1A1 (0.71)	LMNAALDH1A1PNMTMAPTNPSR1
	SCHEMBL4070908	0.81	LMNA (0.71)	LMNAALDH1A1PNMTMAPTNPSR1
	SCHEMBL31143809	0.81	LMNA (0.71)	LMNAALDH1A1PNMTMAPTNPSR1
	SCHEMBL19807188	0.81	LMNA (1.00)	LMNAALDH1A1PNMTMAPTNPSR1
	SCHEMBL31143677	0.80	HDAC3 (0.60)	LMNAALDH1A1ADAMTS5MMP1MMP2
	SCHEMBL13067085	0.80	LMNA (0.45)	LMNAALDH1A1PNMTADAMTS5MAPT
	SCHEMBL29039642	0.79	ALDH1A1 (0.57)	LMNAALDH1A1PNMTADAMTS5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.