Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114882 | 0.80 | TLR7 (0.34) | ALDH1A1GAAHTTMAPTMAPK1 | |
| SCHEMBL8127295 | 0.79 | LMNA (0.42) | GAAMAPTKMT2ATP53POLB | |
| SCHEMBL9045533 | 0.75 | AR (0.31) | ALDH1A1HTTMAPTMAPK1PTGS2 | |
| SCHEMBL8127829 | 0.75 | PDE4A (0.36) | ALDH1A1GAAHTTMAPTKMT2A | |
| SCHEMBL8123311 | 0.75 | MAPT (0.40) | ALDH1A1GAAMAPTMAPK1PTGS2 | |
| SCHEMBL4302908 | 0.73 | ALOX5 (0.38) | ALDH1A1GAAMAPTKMT2APOLB | |
| SCHEMBL28306189 | 0.68 | ALDH1A1 (0.53) | ALDH1A1GAAHTTCRHBPCRHR2 | |
| SCHEMBL842730 | 0.67 | TLR7 (0.42) | ALDH1A1GAAHTTMAPTMAPK1 | |
| SCHEMBL7824056 | 0.66 | CYP3A4 (0.36) | GAAHTTMAPTMAPK1KMT2A | |
| SCHEMBL28511396 | 0.66 | KMT2A (0.67) | ALDH1A1GAAHTTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708772-B1 | IMIDAZO [4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING & MFG (US) | 2000-08-23 | — | — | EP | disclosed |