Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8114882 | 0.94 | TLR7 (0.34) | ARTLR7MAPTPTGS2MAPK1 | |
| SCHEMBL8123311 | 0.81 | MAPT (0.40) | MAPTPTGS2MAPK1TDP1L3MBTL1 | |
| SCHEMBL8127295 | 0.77 | LMNA (0.42) | MAPT | |
| SCHEMBL8127293 | 0.75 | ALDH1A1 (0.43) | MAPTPTGS2MAPK1TDP1L3MBTL1 | |
| SCHEMBL8128780 | 0.74 | MAPT (0.33) | MAPTMAPK1TDP1L3MBTL1DPP4 | |
| SCHEMBL6218914 | 0.73 | MAPT (0.41) | TLR7MAPTPTGS2MAPK1TDP1 | |
| SCHEMBL8127829 | 0.73 | PDE4A (0.36) | MAPTTDP1L3MBTL1ALDH1A1HTT | |
| SCHEMBL842730 | 0.71 | TLR7 (0.42) | TLR7MAPTMAPK1TDP1ALDH1A1 | |
| SCHEMBL4302908 | 0.71 | ALOX5 (0.38) | MAPTTDP1L3MBTL1ALDH1A1 | |
| SCHEMBL5827758 | 0.69 | MAPT (0.41) | MAPTMAPK1TDP1L3MBTL1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708772-A1 | IMIDAZO [4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002597-A1 | IMIDAZO[4,5-c]PYRIDIN-4-AMINES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-01-26 | — | — | WO | disclosed |