SCHEMBL812808

SCHEMBL812808

[C-]#[N+]C(C(C)=O)=C(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.48
CES1 P23141 4/20 0.48
TSHR P16473 3/20 0.39
DAO P14920 1/20 0.39
NAPRT Q6XQN6 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ESR1 P03372 1/20 0.38
CYP19A1 P11511 2/20 0.38
PTGS2 P35354 1/20 0.37
MAPT P10636 2/20 0.37
POLB P06746 1/20 0.37
CYP3A4 P08684 1/20 0.37
PARP1 P09874 1/20 0.37
CYP2C19 P33261 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12341639 0.84 CES1 (0.48) CES2CES1TSHRDAONAPRT
SCHEMBL13260438 0.83 CES1 (0.42) CES2CES1TSHRDAONAPRT
SCHEMBL9002765 0.79 TSHR (0.47) CES2CES1TSHRMAPTCYP3A4
SCHEMBL812849 0.78 CES2 (0.50) CES2CES1TSHRALDH1A1ESR1
SCHEMBL9002586 0.75 SMN1; SMN2 (0.43) TSHRALDH1A1MAPTCYP3A4TDP1
SCHEMBL9002769 0.75 ALDH1A1 (0.51) TSHRALDH1A1CYP19A1MAPTSMN1; SMN2
SCHEMBL12253183 0.75 LMNA (0.39) CES2CES1TSHRCYP19A1MAPT
SCHEMBL13260412 0.74 ESR1 (0.43) CES2CES1TSHRDAONAPRT
SCHEMBL11390780 0.68 CES2 (0.54) CES2CES1TSHRDAONAPRT
SCHEMBL27296008 0.68 CES2 (0.54) CES2CES1TSHRDAONAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9726932-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2017-08-08 US disclosed
US-20160231606-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2016-08-11 US disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 US disclosed
US-9348177-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-9195090-B2 Polymer film, optically-compensatory film, process for producing the same, polarizing plate and liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-11-24 US disclosed
US-20150309348-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2015-10-29 US disclosed
US-9097837-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2015-08-04 US disclosed
US-9091804-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2015-07-28 US disclosed
US-20140377528-A1 OPTICAL FILM, OPTICAL COMPENSATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
US-8823909-B2 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-7318951-B2 Retardation film, producing process thereof and liquid crystal display utilizing the same FUJIFILM CORPORATION (JP) 2008-01-15 US disclosed
US-20070292635-A1 Optical Compensation Polarizing Plate, Image Display Unit and Liquid Crystal Display Unit FUJIFILM CORPORATION (JP) 2007-12-20 US disclosed
US-20070285603-A1 Transparent Film And Optical Compensatory Film, Polarizing Plate And Liquid-Crystal Display Device Employing It FUJI PHOTO FILM CO., LTD. (JP) 2007-12-13 US disclosed
US-20070273815-A1 Cellulose acylate film, production method of cellulose acylate film, optically-compensatory film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2007-11-29 US disclosed
US-20070252293-A1 METHOD FOR MANUFACTURING AN OPTICAL FILM HAVING A CONVEXOCONCAVE STRUCTURE, OPTICAL FILM, WIRE GRID POLARIZER AND RETARDATION FILM KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
US-20070092663-A1 Cellulose ester film, polarizing plate and display KONICA MINOLTA OPTO, INC. 2007-04-26 US disclosed
US-20070076155-A1 Optical film, optical compensation film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-04-05 US disclosed
US-20070059458-A1 Cellulose acylate film, optically compensatory film, polarizing plate and liquid crystal display FUJI PHOTO FILM CO., LTD. (JP) 2007-03-15 US disclosed
US-20070048458-A1 Optical film, method of producing the same, optical compensatory film, polarizing film, and liquid crystal display device FUJI PHOTO FILM CO., LTD. (JP) 2007-03-01 US disclosed
US-20070040962-A1 Optical resin film and polarizing plate and liquid crystal display using same FUJI PHOTO FILM CO., LTD. (JP) 2007-02-22 US disclosed