SCHEMBL812845

SCHEMBL812845

CC(N)(O)N1CCNCC1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
HPGD P15428 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16719167 0.79 CA2 (0.32) CA12CA1CA2CA9
SCHEMBL8078414 0.79 ADRB1 (0.31)
SCHEMBL15472 0.79 SIGMAR1 (0.33) OPRD1SIGMAR1HPGDCA12CA1
SCHEMBL9363442 0.79 ADRB1 (0.31)
SCHEMBL710061 0.79 SIGMAR1 (0.33) OPRD1SIGMAR1HPGDCA12CA1
SCHEMBL467885 0.79 ADRB1 (0.31)
SCHEMBL30608917 0.76
SCHEMBL1070718 0.75 OPRD1 (0.32) OPRD1SIGMAR1HPGDCA12CA1
SCHEMBL27694605 0.75 OPRD1 (0.32) OPRD1SIGMAR1HPGDCA12CA1
SCHEMBL8370582 0.75 SIGMAR1 (0.33) SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230106817-A1 SILICA-REINFORCED RUBBER COMPOSITIONS AND ARTICLES MADE THEREFROM MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2023-04-06 US disclosed
CN-105579475-B Low vinyl bond modified elastomeric copolymers 盛禧奥欧洲有限责任公司 2018-11-02 CN disclosed
EP-3049447-B1 LOW VINYL BOND MODIFIED ELASTOMERIC COPOLYMERS TRINSEO EUROPE GMBH (CH) 2018-06-27 EP disclosed
EP-2283046-B1 MODIFIED ELASTOMERIC POLYMERS TRINSEO EUROPE GMBH (CH) 2016-10-19 EP disclosed
CN-105980537-A Long lasting freshening compositions 宝洁公司 2016-09-28 CN disclosed
US-20160222138-A1 Low Vinyl Bond Modified Elastomeric Copolymers SYNTHOS DWORY 7 SPOLKA Z OGRANICZONA ODPOWIEDZIALNOSCIA (PL) 2016-08-04 US disclosed
EP-3049447-A1 LOW VINYL BOND MODIFIED ELASTOMERIC COPOLYMERS Styron Europe GmbH (CH) 2016-08-03 EP disclosed
CN-105579475-A Low vinyl bond modified elastomeric copolymers STYRON EUROPE GMBH 2016-05-11 CN disclosed
WO-2015043660-A1 LOW VINYL BOND MODIFIED ELASTOMERIC COPOLYMERS STYRON EUROPE GMBH (CH) 2015-04-02 WO disclosed
US-20150087768-A1 Elastomeric Polymer Compositions STYRON EUROPE GMBH (CH) 2015-03-26 US disclosed
EP-0924227-B1 Conjugated diolefin-based copolymer rubber and composition thereof JSR CORP (JP) 2004-03-10 EP disclosed
US-20030125448-A1 A butadiene-styrene copolymer having end terminals modified with a tin compound and amino compound; molecular weight distribution, tire rolling resistance, hysteresis-free, wear resistance GOODYEAR TIRE & RUBBER COMPANY, THE 2003-07-03 US disclosed
EP-1318172-A1 Pneumatic tire having a rubber component containing a tin/amino functionalized rubber and an inversion carbon black THE GOODYEAR TIRE & RUBBER COMPANY (US) 2003-06-11 EP disclosed
EP-1000970-B1 Polymodal conjugated diolefin vinyl aromate rubber composition JSR CORP (JP) 2003-05-02 EP disclosed
US-6362272-B1 CONJUGATED DIOLEFIN AND AROMATIC VINYL COPOLYMER JSR CORPORATION (JP) 2002-03-26 US disclosed
US-6344518-B1 Conjugated diolefin copolymer rubber and rubber composition JSR CORPORATION (JP) 2002-02-05 US disclosed
US-6191234-B1 CONJUGATED DIENE-AROMATIC VINYL COPOLYMER OBTAINED BY MODIFYING POLYMER WITH A AMINO GROUP IS USED TO IMPROVE WET SKID RESISTANCE, WEAR RESISTANCE OF AUTOMOBILE TIRE TREAD JSR CORPORATION (JP) 2001-02-20 US disclosed
EP-1000970-A1 Polymodal conjugated diolefin vinyl aromate rubber composition JSR Corporation (JP) 2000-05-17 EP disclosed
EP-0992537-A1 Oil extended rubber and rubber composition JSR Corporation (JP) 2000-04-12 EP disclosed
EP-0924227-A1 Conjugated diolefin-based copolymer rubber and composition thereof JSR Corporation (JP) 1999-06-23 EP disclosed