Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.30 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15472 | 0.83 | SIGMAR1 (0.33) | SIGMAR1OPRD1HPGDCA2CA12 | |
| SCHEMBL27694605 | 0.79 | OPRD1 (0.32) | SIGMAR1OPRD1HPGDCA2CA12 | |
| SCHEMBL1070718 | 0.79 | OPRD1 (0.32) | SIGMAR1OPRD1HPGDCA2CA12 | |
| SCHEMBL812845 | 0.79 | OPRD1 (0.32) | SIGMAR1OPRD1HPGDCA2CA12 | |
| SCHEMBL6556071 | 0.77 | ADRB1 (0.33) | SIGMAR1HPGDADRB1 | |
| SCHEMBL104919 | 0.77 | ADRB1 (0.33) | SIGMAR1OPRD1HPGDADRB1 | |
| SCHEMBL9582917 | 0.77 | ADRB1 (0.33) | SIGMAR1HPGDADRB1 | |
| SCHEMBL10540756 | 0.77 | CA2 (0.35) | SIGMAR1HPGDCA2CA12CA1 | |
| SCHEMBL3888868 | 0.77 | ADRB1 (0.33) | SIGMAR1OPRD1HPGDADRB1 | |
| SCHEMBL28210518 | 0.75 | SIGMAR1 (0.33) | SIGMAR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 367 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4585590-A1 | METHOD FOR RECOVERING HYDROXYETHYL PIPERAZINE | BASF SE (DE) | 2025-07-16 | — | — | EP | claimed |
| CN-118893079-A | Recovery method of polyester/wool blended fabric | 青岛阿脒诺材料技术有限公司 | 2024-11-05 | — | — | CN | claimed |
| CN-118681369-A | Ternary mixed amine absorbent, preparation method thereof and application thereof in magnesite calcination flue gas treatment | 辽宁信宇热能技术工程有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-113056458-B | Production of hydroxyethyl piperazine | 陶氏环球技术有限责任公司 | 2024-05-24 | — | — | CN | claimed |
| US-11987562-B2 | Production of hydroxyethylpiperazine | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-05-21 | — | — | US | claimed |
| EP-3873886-B1 | PRODUCTION OF HYDROXYETHYLPIPERAZINE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-03-20 | — | — | EP | claimed |
| CN-117046266-A | Absorbent for cooperatively capturing sulfur dioxide and carbon dioxide and method for capturing sulfur dioxide and carbon dioxide in flue gas | 中国恩菲工程技术有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-116438284-A | Microelectronic device cleaning compositions | 恩特格里斯公司 | 2023-07-14 | — | — | CN | claimed |
| CN-115991528-A | Method for purifying flue gas absorbent | 河北精致科技有限公司 | 2023-04-21 | — | — | CN | claimed |
| US-11253811-B2 | Process for reducing energy consumption in the regeneration of hybrid solvents | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-02-22 | — | — | US | claimed |
| EP-1252151-B1 | A PROCESS FOR THE PREPARATION OF QUETIAPINE AND INTERMEDIATES THEREFOR | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 2004-03-17 | — | — | EP | claimed |
| EP-0821664-B1 | METHOD FOR PRODUCING AMINOETHYLETHANOLAMINE AND/OR HYDROXYETHYL PIPERAZINE | AKZO NOBEL NV (NL) | 2000-04-05 | — | — | EP | claimed |
| EP-0290862-B1 | Process for the preparation of 1,4-diazabicyclo[2.2.2] octanes | BASF Aktiengesellschaft (DE) | 1993-06-23 | — | — | EP | claimed |
| EP-0263463-B1 | Process for the preparation of 1,4-diazabicyclo[2,2,2] octanes | BASF Aktiengesellschaft (DE) | 1992-03-25 | — | — | EP | claimed |
| US-4837324-A | Process for the reaction of piperazine, and derivatives thereof, with glyoxal, and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1989-06-06 | — | — | US | claimed |
| EP-0310689-A1 | Process for the preparation of 1,4-diazabicyclo(2,2,2)-octanes | BASF Aktiengesellschaft (DE) | 1989-04-12 | — | — | EP | claimed |
| US-4804758-A | FROM HETEROCYCLIC AMINES USING BORON OR IRON SILICATE ZEOLITE CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | claimed |
| EP-0290862-A2 | Process for the preparation of 1,4-diazabicyclo[2.2.2] octanes | BASF Aktiengesellschaft (DE) | 1988-11-17 | — | — | EP | claimed |
| US-4757143-A | Treating hydroxyethyl ethyleneamine feedstock with cyclization catalyst | TEXACO INC. (US) | 1988-07-12 | — | — | US | claimed |
| EP-0263463-A2 | Process for the preparation of 1,4-diazabicyclo[2,2,2] octanes | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11987562-B2 | Production of hydroxyethylpiperazine | HAMP, HTR5A, HTR2A | SIGMAR1 221/4885OPRD1 368/4885HPGD 41/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.