Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613564 | 0.91 | ESR2 (0.45) | ESR2SLC6A9DCLRE1BCTSAFFAR1 | |
| SCHEMBL7102811 | 0.86 | SLC6A9 (0.39) | ESR2SLC6A9MRGPRX4PPARGPPARD | |
| SCHEMBL7248442 | 0.80 | ESR2 (0.51) | ESR2SLC6A9MRGPRX4PPARGPPARD | |
| SCHEMBL6049534 | 0.77 | TDP1 (0.49) | MRGPRX4FFAR1MAPT | |
| SCHEMBL21922956 | 0.70 | ESR1 (0.40) | ESR2 | |
| SCHEMBL22641753 | 0.69 | ESR1 (0.41) | ESR2 | |
| SCHEMBL22238733 | 0.69 | ESR1 (0.41) | ESR2 | |
| SCHEMBL10024224 | 0.68 | DCLRE1B (0.61) | ESR2DCLRE1B | |
| SCHEMBL7571401 | 0.67 | PPARG (0.52) | SLC6A9MRGPRX4PPARGPPARDPPARA | |
| SCHEMBL4602328 | 0.67 | PTPN11 (0.56) | SLC6A9DCLRE1BCTSAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8058210-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER CROPSCIENCE AG (DE) | 2011-11-15 | — | — | US | disclosed |
| US-7718706-B2 | Arylphenyl-substituted cyclic keto-enols | BAYER AKTIENGESELLSCHAFT (DE) | 2010-05-18 | — | — | US | disclosed |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | LIEB FOLKER | 2010-04-08 | — | — | US | disclosed |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | LIEB FOLKER | 2008-04-03 | — | — | US | disclosed |
| US-7288676-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-10-30 | — | — | US | disclosed |
| US-7105471-B2 | Arylphenyl-substituted cyclic ketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2006-09-12 | — | — | US | disclosed |
| US-20060122061-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER | 2006-06-08 | — | — | US | disclosed |
| US-20040167031-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2004-08-26 | — | — | US | disclosed |
| US-6716832-B2 | PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | disclosed |
| US-20020188136-A1 | Arylphenyl-substituted cyclic ketoenols | LIEB FOLKER (DE) | 2002-12-12 | — | — | US | disclosed |
| US-6417370-B1 | HERBICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122061-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, KCNQ3, KCNQ2 | ESR2 1670/4885SLC6A9 2773/4885MRGPRX4 2184/4885 |
| US-20080081807-A1 | Arylphenyl-substituted cyclic keto-enols | KCNE1, DDT, KCNQ3 | ESR2 1810/4885SLC6A9 2823/4885MRGPRX4 2812/4885 |
| US-20100087320-A1 | ARYLPHENYL-SUBSTITUTED CYCLIC KETO-ENOLS | KCNE1, DDT, KCNQ3 | ESR2 1810/4885SLC6A9 2823/4885MRGPRX4 2812/4885 |
| US-20040167031-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP21A2, KCNQ3 | ESR2 1371/4885SLC6A9 2820/4885MRGPRX4 2214/4885 |
| US-20020188136-A1 | Arylphenyl-substituted cyclic ketoenols | KCNE1, CYP21A2, KCNQ3 | ESR2 1398/4885SLC6A9 2850/4885MRGPRX4 2173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.