Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9058109 | 0.86 | KMT2A (0.55) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8129491 | 0.84 | KMT2A (0.62) | SMN1; SMN2RAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL7096104 | 0.82 | EPHX1 (0.55) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8130235 | 0.80 | RAB9A (0.67) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8138188 | 0.79 | LNPEP (0.57) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8134790 | 0.78 | LMNA (0.53) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8138192 | 0.77 | ROCK2 (0.50) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8122584 | 0.76 | KMT2A (0.57) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8130037 | 0.73 | CNR1 (0.58) | MAPTSMN1; SMN2RAB9ANPC1KMT2A | |
| SCHEMBL8121260 | 0.73 | HTT (0.56) | MAPTSMN1; SMN2RAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720601-A1 | GASTRIN AND CCK RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995004720-A2 | GASTRIN AND CCK RECEPTOR LIGANDS | BLACK JAMES FOUNDATION (GB) | 1995-02-16 | — | — | WO | disclosed |