Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 4/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148381 | 0.89 | IARS1 (0.34) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL8120553 | 0.89 | MGAM (0.35) | MGAMGAASIMGAM2CYP1A2 | |
| SCHEMBL8119566 | 0.85 | DPP4 (0.39) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL8126516 | 0.84 | MGAM (0.35) | MGAMGAASIMGAM2DPP4 | |
| SCHEMBL8120903 | 0.82 | DPP4 (0.37) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL8121069 | 0.81 | DPP4 (0.36) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL8131712 | 0.80 | SLC15A1 (0.52) | CYP1A2ALDH1A1 | |
| SCHEMBL3727783 | 0.79 | MMP1 (0.36) | MGAMGAASIMGAM2DPP4 | |
| SCHEMBL3727785 | 0.79 | MMP1 (0.36) | MGAMGAASIMGAM2DPP4 | |
| SCHEMBL8129583 | 0.78 | DPP4 (0.39) | DPP4DPP8DPP9DPP7IARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054891-A1 | PRODRUGS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999041275-A1 | PRODRUGS | MEDIVIR AB (SE) | 1999-08-19 | — | — | WO | disclosed |